Evidence map›Paper›PMID 25957977›Full record

GuidelineThe Journal of pediatrics2015

Recommendations from the Pediatric Endocrine Society for Evaluation and Management of Persistent Hypoglycemia in Neonates, Infants, and Children.

Paul S Thornton, Charles A Stanley, Diva D De Leon, Deborah Harris, Morey W Haymond, Khalid Hussain, Lynne L Levitsky, Mohammad H Murad, Paul J Rozance, Rebecca A Simmons and 5 more

3 registry-linked trialsAbstract readPractice Guideline
In one paragraph

Guideline in The Journal of pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 228 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
228citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04353713 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Oral Dextrose Gel to Prevent Early Hypoglycaemia in Very Preterm Infants

TypeinterventionalSponsorUniversity College DublinRan2020 to 2022Enrolled534ConditionsHypoglycemia in Newborn InfantsArms40% Dextrose Gel, 2% carboxymethylcellulose gel
NCT07015450 phase4completednot on this mapstarted 2023, after this paper: background citation

The Efficacy of Self-Manufactured 40% Dextrose Gel as Supplementary to Asymptomatic Transient Neonatal Hypoglycemia Treatment : A Randomized Controlled Trial

TypeinterventionalSponsorIndonesia UniversityRan2023 to 2023Enrolled133ConditionsNeonatal HypoglycemiaArmsself-manufactured 40% dextrose gel, Standard therapy
NCT07533318 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Study of Endocrine, Metabolic, and Genetic Risk Factors of Pediatric Persistent Hypoglycemia at Sohag University Hospital

TypeobservationalSponsorSohag UniversityRan2026 to 2028Enrolled50ConditionsHypoglycaemia
3 · Its place in the literature

Who cites it

228 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Guideline
  4. Oral dextrose gel for the treatment of hypoglycaemia in newborn infants.The Cochrane database of systematic reviews · 2022
    Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Two-year outcomes after dextrose gel prophylaxis for neonatal hypoglycaemia.Archives of disease in childhood. Fetal and neonatal edition · 2021
    Trial
  10. Article
  11. Family with two novelClinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2026
    Article
  12. Review
  13. Article
  14. Neonatal hypoglycemia screening practices in infants born to mothers without glucose tolerance testing.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  15. Prevalence and safety of diazoxide in the neonatal intensive care unit.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  16. Sweeter recovery, less intravenous fluids: a NICU quality improvement initiative for managing neonatal hypoglycemia.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  17. Article
  18. Article
  19. Article
  20. Review

168 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Paul S ThorntonDivision of Endocrinology, Cook Children's Medical Center, Fort Worth, TX. Electronic address: Paul.thornton@cookchildrens.org.
Charles A StanleyDivision of Endocrinology, The Children's Hospital of Philadelphia, Philadelphia, PA.
Diva D De LeonDivision of Endocrinology, The Children's Hospital of Philadelphia, Philadelphia, PA.
Deborah HarrisNewborn Intensive Care Unit, Waikato District Health Board, Hamilton, New Zealand.
Morey W HaymondChildren's Nutrition Research Center, Texas Children's Hospital, Houston, TX.
Khalid HussainDepartment of Endocrinology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.
Lynne L LevitskyPediatric Endocrine Unit, Massachusetts General Hospital, Boston, MA.
Mohammad H MuradDivision of Preventive Medicine, Mayo Clinic, Rochester, MN.
Paul J RozanceDivision of Neonatology, University of Colorado School of Medicine, Aurora, CO.
Rebecca A SimmonsDivision of Neonatology, The Children's Hospital of Philadelphia, Philadelphia, PA.
Mark A SperlingDivision of Endocrinology, Diabetes and Metabolism, Children's Hospital of Pittsburgh, Pittsburgh, PA.
David A WeinsteinGlycogen Storage Disease Program, University of Florida College of Medicine, Gainesville, FL.
Neil H WhiteDepartment of Pediatrics and Medicine, Washington University in St Louis, St Louis, MO.
Joseph I WolfsdorfDivision of Endocrinology, Boston Children's Hospital, Boston, MA.
Pediatric Endocrine Society

Funding

Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI Rebecca A Simmons · 2006 to 2026
$35.3M
Nutrient Coordination of Pancreatic Vasculature and Beta-CellsR01DK088139 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI ROZANCE, PAUL JOSEPH · 2011 to 2020
$5.1M
MECHANISMS BY WHICH IUGR LEADS TO DIABETESR01DK055704 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI SIMMONS, REBECCA A · 2000 to 2014
$3.6M
NIDDK NIH HHS R01 DK055704NIDDK NIH HHS R01 DK088139NIEHS NIH HHS P30 ES013508
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Blood GlucoseChildChild, PreschoolEndocrinologyHumansHypoglycemiaInfantInfant, NewbornPediatricsSocieties, MedicalBlood Glucose

Identifiers

PMID25957977
PMCPMC11891912

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.