Evidence map›Paper›PMID 25957303›Full record

ReviewCold Spring Harbor perspectives in biology2015

Schwann Cells: Development and Role in Nerve Repair.

Kristján R Jessen, Rhona Mirsky, Alison C Lloyd

Open access · bronzeAbstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 416 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
416citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

416 citing papers in PubMed, 1 synthesis or guideline pooled it, 732 citations in OpenAlex.

  1. Pooled it
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  12. Control of Schwann Cell Myelination by DDR1 Receptor Tyrosine Kinase.International journal of molecular sciences · 2026
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356 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kristján R JessenDepartment of Cell and Developmental Biology, University College London, London WC1E 6BT, United Kingdom.
Rhona MirskyDepartment of Cell and Developmental Biology, University College London, London WC1E 6BT, United Kingdom.
Alison C LloydMRC Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, United Kingdom.
University College London · GB

Funding

Cancer Research UK 11244Cancer Research UK 17135Medical Research Council G0600967Wellcome TrustWorldwide Cancer Research 12-0041
6 · The paper itself

Abstract

Schwann cells develop from the neural crest in a well-defined sequence of events. This involves the formation of the Schwann cell precursor and immature Schwann cells, followed by the generation of the myelin and nonmyelin (Remak) cells of mature nerves. This review describes the signals that control the embryonic phase of this process and the organogenesis of peripheral nerves. We also discuss the phenotypic plasticity retained by mature Schwann cells, and explain why this unusual feature is central to the striking regenerative potential of the peripheral nervous system (PNS).

Indexed as

Models, BiologicalAnimalsCell ProliferationMiceNerve RegenerationNeural CrestPeripheral NervesRatsSchwann Cells

Identifiers

PMID25957303
PMCPMC4484967
OpenAlexW2102232105

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.