Evidence map›Paper›PMID 25957010›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2016

Interval versus continuous aerobic exercise training in breast cancer survivors--a pilot RCT.

Lianne B Dolan, Kristin Campbell, Karen Gelmon, Sarah Neil-Sztramko, Daniel Holmes, Donald C McKenzie

Abstract read
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In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 18 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 18 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 18 syntheses or guidelines pooled it.

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  9. Rates of compliance and adherence to high-intensity interval training: a systematic review and Meta-analyses.The international journal of behavioral nutrition and physical activity · 2023
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  16. Short-Term (<8 wk) High-Intensity Interval Training in Diseased Cohorts.Medicine and science in sports and exercise · 2018
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  17. Physical activity for women with breast cancer after adjuvant therapy.The Cochrane database of systematic reviews · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lianne B DolanSchool of Kinesiology, University of British Columbia, Vancouver, BC, Canada. lbdolan@alumni.ubc.ca.
Kristin CampbellDepartment of Physical Therapy, University of British Columbia, Vancouver, BC, Canada.
Karen GelmonDepartment of Medical Oncology, British Columbia Cancer Agency, Vancouver, BC, Canada.
Sarah Neil-SztramkoSchool of Population and Public Health, University of British Columbia, Vancouver, BC, Canada.
Daniel HolmesDepartment of Pathology and Laboratory Medicine, St. Paul's Hospital Vancouver British Columbia, Vancouver, Canada.
Donald C McKenzieSchool of Kinesiology, University of British Columbia, Vancouver, BC, Canada.

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

backgroundExercise therapy is being explored in a variety of cancer populations to counteract treatment-related deconditioning. Higher intensity interval protocols are being prescribed to improve physical function and attenuate surrogates of comorbidity in non-cancer populations. The purpose of this study is to explore the safety of higher intensity exercise stimuli on cardiorespiratory fitness (VO2peak) in breast cancer survivors.

methodsPostmenopausal breast cancer survivors were randomized into three groups: supervised aerobic interval training (AIT), supervised continuous moderate exercise training (CMT), and an unsupervised control group (CON). For 6 weeks, AIT exercised between 70 and 100% VO2peak, while CMT exercised between 60 and 70% VO2peak. Both groups followed a matched-work design.

resultsThirty-three participants completed the study (age, 57.2 (9) years; weight, 67.6 (12) kg) with no adverse advents. Between-group baseline values were non-significant. VO2peak at baseline (25.3 (5.4) mL·kg(-1)·min(-1)) was below population norms. Compared to CON, cardiorespiratory fitness improved in AIT and CMT by 12% (P < 0.001) with no significant difference between exercise groups. AIT had a greater influence on lower extremity strength (P = 0.026) and body weight (P = 0.031).

conclusionThis pilot study provides evidence that similar to CMT, AIT can safely increase VO2peak in a small group of breast cancer survivors. Further exploration of the benefits of implementing higher intensity training protocols is warranted.

Indexed as

Breast NeoplasmsExerciseExercise TherapyFemaleHumansMiddle AgedPilot ProjectsSurvivorsAerobic capacityBlood biomarkersExercise intensityNeoplasmRehabilitationSurvivorship

Identifiers

PMID25957010

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.