ArticleBMC genomics2015
Classification of fungal and bacterial lytic polysaccharide monooxygenases.
Article in BMC genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed.
- Genomic Insights into the Probiotic Potential of Lactic Acid Bacteria Isolated from Tocosh: Traditional Peruvian Fermented Potatoes.International journal of molecular sciences · 2026Article
- Integrative phylogenomic and pangenome landscape of Bacillus: insights from 10,000 genomes into taxonomy, functional potential, and biotechnological applications.World journal of microbiology & biotechnology · 2026Article
- The chitinolytic enzymes from the entomopathogenic fungusFrontiers in fungal biology · 2026Review
- Improved genome assembly of Onygena corvina, a keratin-degrading fungus.BMC research notes · 2025Article
- Characterization of a unique polysaccharide monooxygenase from the plant pathogenProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Closing the Nutrient Loop-The New Approaches to Recovering Biomass Minerals during the Biorefinery Processes.International journal of environmental research and public health · 2023Review
- Reliable and Scalable Identification and Prioritization of Putative Cellulolytic Anaerobes With Large Genome Data.Frontiers in bioinformatics · 2022Article
- Basidiomycota Fungi and ROS: Genomic Perspective on Key Enzymes Involved in Generation and Mitigation of Reactive Oxygen Species.Frontiers in fungal biology · 2022Review
- Keratinases as Versatile Enzymatic Tools for Sustainable Development.Biomolecules · 2021Review
- Exceptionally rich keratinolytic enzyme profile found in the rare actinomycetes Amycolatopsis keratiniphila D2Applied microbiology and biotechnology · 2021Review
- LPMO-oxidized cellulose oligosaccharides evoke immunity in Arabidopsis conferring resistance towards necrotrophic fungus B. cinerea.Communications biology · 2021Article
- Chitin- and Keratin-Rich Soil Amendments Suppress Rhizoctonia solani Disease via Changes to the Soil Microbial Community.Applied and environmental microbiology · 2021Article
- Structure, Application, and Biochemistry of Microbial Keratinases.Frontiers in microbiology · 2021Review
- Identification and characterization of a novel AA9-type lytic polysaccharide monooxygenase from a bagasse metagenome.Applied microbiology and biotechnology · 2021Article
- Microbial enzymes catalyzing keratin degradation: Classification, structure, function.Biotechnology advances · 2020Review
- Plant-microbiome interactions: from community assembly to plant health.Nature reviews. Microbiology · 2020Review
- Novel keratinolytic enzymes, discovered from a talented and efficient bacterial keratin degrader.Scientific reports · 2020Article
- Database Mining for Novel Bacterial β-Etherases, Glutathione-Dependent Lignin-Degrading Enzymes.Applied and environmental microbiology · 2020Article
- Genome-wide annotation, comparison and functional genomics of carbohydrate-active enzymes in legumes infectingMycology · 2020Article
- Specific Xylan Activity Revealed for AA9 Lytic Polysaccharide Monooxygenases of the Thermophilic FungusApplied and environmental microbiology · 2019Article
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2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundLytic polysaccharide monooxygenases are important enzymes for the decomposition of recalcitrant biological macromolecules such as plant cell wall and chitin polymers. These enzymes were originally designated glycoside hydrolase family 61 and carbohydrate-binding module family 33 but are now classified as auxiliary activities 9, 10 and 11 in the CAZy database. To obtain a systematic analysis of the divergent families of lytic polysaccharide monooxygenases we used Peptide Pattern Recognition to divide 5396 protein sequences resembling enzymes from families AA9 (1828 proteins), AA10 (2799 proteins) and AA11 (769 proteins) into subfamilies.
resultsThe results showed that the lytic polysaccharide monooxygenases have two conserved regions identified by conserved peptides specific for each AA family. The peptides were used for in silico PCR discovery of the lytic polysaccharide monooxygenases in 79 fungal and 95 bacterial genomes. The bacterial genomes encoded 0-7 AA10s (average 0.6). No AA9 or AA11 were found in the bacteria. The fungal genomes encoded 0-40 AA9s (average 7) and 0-15 AA11s (average 2) and two of the fungi possessed a gene encoding a putative AA10. The AA9s were mainly found in plant cell wall-degrading asco- and basidiomycetes in agreement with the described role of AA9 enzymes. In contrast, the AA11 proteins were found in 36 of the 39 ascomycetes and in only two of the 32 basidiomycetes and their abundance did not correlate to the degradation of cellulose and hemicellulose.
conclusionsThese results provides an overview of the sequence characteristics and occurrence of the divergent AA9, AA10 and AA11 families and pave the way for systematic investigations of the of lytic polysaccharide monooxygenases and for structure-function studies of these enzymes.
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