Evidence map›Paper›PMID 25956073›Full record

ReviewPulmonary pharmacology & therapeutics2015

The risk and outcomes of pneumonia in patients on inhaled corticosteroids.

Oriol Sibila, Natalia Soto-Gomez, Marcos I Restrepo

Abstract readReview
In one paragraph

Review in Pulmonary pharmacology & therapeutics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Aerosol pulmonary immune engineering.Advanced drug delivery reviews · 2023
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Oriol SibilaServei de Pneumologia, Hospital de la Santa Creu i Sant Pau, Sant Antoni Maria Claret 167, 08025 Barcelona, Spain; Institut d'Investigació Biomèdica Sant Pau (IBB Sant Pau), Sant Antoni Maria Claret, 167 Pavelló de Sant Frederic, Planta 1, 08025 Barcelona, Spain. Electronic address: OSibila@santpau.cat.
Natalia Soto-GomezSouth Texas Veterans Health Care System, 7400 Merton Minter Boulevard, San Antonio, TX 78229, United States; University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, San Antonio, TX 78229, United States. Electronic address: sotogomez@uthscsa.edu.
Marcos I RestrepoSouth Texas Veterans Health Care System, 7400 Merton Minter Boulevard, San Antonio, TX 78229, United States; University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, San Antonio, TX 78229, United States. Electronic address: restrepom@uthscsa.edu.

Funding

Institute for Integration of Medicine & Science: A Partnership to Improve HealthUL1TR001120 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CLARK, ROBERT A, HARGREAVES, KENNETH M · 2013 to 2017
$16.5M
Institute for Integration of Medicine & Science: A Partnership to Improve HealthKL2TR001118 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CLARK, ROBERT A, DOUGHERTY, DONALD M · 2013 to 2017
$3.4M
Effect of macrolides as immunomodulators in patients with sepsis and pneumoniaK23HL096054 · NHLBI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI RESTREPO, MARCOS I. · 2010 to 2014
$689k
NCATS NIH HHS KL2 TR001118NCATS NIH HHS UL1 TR001120NHLBI NIH HHS K23 HL096054NHLBI NIH HHS K23HL096054
6 · The paper itself

Abstract

Corticosteroids are frequently prescribed anti-inflammatory medications. Inhaled corticosteroids (ICS) are indicated for Chronic Obstructive Pulmonary Disease (COPD) and asthma. ICS are associated with a decrease in exacerbations and improved quality of life in COPD, however multiple studies have linked the chronic use of ICSs with an increased risk of developing pneumonia, though the effect on mortality is unclear. We review the association of ICS with the risk of pneumonia and the implications on clinical outcomes.

Indexed as

Administration, InhalationAsthmaBronchodilator AgentsGlucocorticoidsHumansPneumoniaPulmonary Disease, Chronic ObstructiveQuality of LifeRiskBronchodilator AgentsGlucocorticoidsChronic obstructive pulmonary diseaseInhaled corticosteroidsPneumonia

Identifiers

PMID25956073
PMCPMC5079105

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.