ArticleEnvironmental health perspectives2015
Prospective Study of Ambient Particulate Matter Exposure and Risk of Pulmonary Embolism in the Nurses' Health Study Cohort.
Article in Environmental health perspectives, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Characteristics of cohort studies of long-term exposure to PMEnvironmental science and pollution research international · 2019Pooled it
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- A review of venous thromboembolism in India.The Indian journal of medical research · 2023Review
- Links between chronic exposure to outdoor air pollution and cardiovascular diseases: a review.Environmental chemistry letters · 2022Review
- A1B and BB blood group genotypes are risk factors for pulmonary embolism.Wiener klinische Wochenschrift · 2021Article
- Seasonal association between ambient fine particulate matter and venous thromboembolism in Beijing, China: a time-series study.Environmental science and pollution research international · 2021Article
- Influence of weather and air pollution on the occurrence of idiopathic pulmonary embolism in the region of Sousse (Tunisia).Environmental science and pollution research international · 2020Article
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- Involvement of fine particulate matter exposure with gene expression pathways in breast tumor and adjacent-normal breast tissue.Environmental research · 2020Article
- Particulate Matter and Traffic-Related Exposures in Relation to Breast Cancer Survival.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2019Article
- Vaginal estrogen use and chronic disease risk in the Nurses' Health Study.Menopause (New York, N.Y.) · 2018Article
- Adiposity throughout the life course and risk of venous thromboembolism.Thrombosis research · 2018Article
- Metabolites Associated With the Risk of Incident Venous Thromboembolism: A Metabolomic Analysis.Journal of the American Heart Association · 2018Article
- Reduction in physical function in women after venous thromboembolism.Journal of thrombosis and haemostasis : JTH · 2018Article
- Does air pollution contribute to travelers' illness and deaths?-evidence from a case report and need for further studies.Journal of travel medicine · 2018Article
- Residential particulate matter and distance to roadways in relation to mammographic density: results from the Nurses' Health Studies.Breast cancer research : BCR · 2017Article
- Long-Term PM2.5 Exposure and Respiratory, Cancer, and Cardiovascular Mortality in Older US Adults.American journal of epidemiology · 2017Article
- Environmental and Genetic Risk Factors Associated with Venous Thromboembolism.Seminars in thrombosis and hemostasis · 2016Review
- Interactions of established risk factors and a GWAS-based genetic risk score on the risk of venous thromboembolism.Thrombosis and haemostasis · 2016Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 3 countries.
Funding
Abstract
backgroundPulmonary embolism (PE) is the most serious manifestation of venous thromboembolism and a leading cause of sudden death. Several studies have suggested associations of venous thromboembolism with short-term particulate matter (PM) exposure; evidence on long-term PM and traffic exposure is mixed.
objectivesWe examined the association of long-term exposure to PM2.5, PM2.5-10, and PM10 (PM with diameter of ≤ 2.5, 2.5-10, and ≤ 10 μm) and distance to roadways with overall incident PE and with PE subtypes in a cohort of U.S. women.
methodsThe study included 115,745 women from the Nurses' Health Study, followed from 1992 through 2008. Incident PE cases were self-reported biennially. Nonidiopathic PE were cases for which the medical record revealed an underlying health condition related to PE (i.e., surgery, trauma, or malignancy); idiopathic PE were cases with no such history. We used spatiotemporal models combining spatial smoothing and geographic covariates to quantify exposure at residential addresses, and Cox proportional hazards models to calculate hazard ratios (HR) and 95% confidence intervals (CIs).
resultsPM2.5 averaged over 1 month (HR = 1.22; 95% CI: 1.04, 1.44) or 12 months (HR = 1.17; 95% CI: 0.93, 1.48) was associated with incident PE, after adjusting for known risk factors and PM2.5-10. Equivalent analyses restricted to PE subtypes showed a positive association for PM2.5 with nonidiopathic PE, but not with idiopathic PE. We did not find evidence of an association between distance to roadways and PE risk.
conclusionsWe provide evidence that PM in the prior 1 and 12 months is associated with PE risk. Our results also suggest that women with underlying health conditions may be more susceptible to PE after PM exposure.
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