ArticlePloS one2015
MAF2 Is Regulated by Temperature-Dependent Splicing and Represses Flowering at Low Temperatures in Parallel with FLM.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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Who cites it
53 citing papers in PubMed, 110 citations in OpenAlex.
- Genetic mechanisms underlying temperature-mediated changes in flower development.Journal of experimental botany · 2026Review
- Dynamic evolution of FLC/MAF-like genes accompanying Brassicaceae radiation.Annals of botany · 2026Article
- Cloning, Expression and Functional Study ofPlants (Basel, Switzerland) · 2026Article
- Article
- STALARD: Selective Target Amplification for Low-Abundance RNA Detection.Plant methods · 2025Article
- Decoding plant thermosensors: mechanism of temperature perception and stress adaption.Frontiers in plant science · 2025Review
- Research progress on delayed flowering under short-day condition inFrontiers in plant science · 2025Review
- Mapping intron retention events contributing to complex traits using splice quantitative trait locus.Plant methods · 2023Article
- Catsnap: a user-friendly algorithm for determining the conservation of protein variants reveals extensive parallelisms in the evolution of alternative splicing.The New phytologist · 2023Article
- A high-quality assembled genome of a representative peach landrace, 'Feichenghongli', and analysis of distinct late florescence and narrow leaf traits.BMC plant biology · 2023Article
- IiSVP of Isatis indigotica can reduce the size and repress the development of floral organs.Plant cell reports · 2023Article
- meLife · 2022Article
- Temperature-mediated flower size plasticity in Arabidopsis.iScience · 2022Article
- Flowering time runs hot and cold.Plant physiology · 2022Review
- Identification and Characterization of the MIKC-Type MADS-Box Gene Family inInternational journal of molecular sciences · 2022Article
- ABA Mediates Plant Development and Abiotic Stress via Alternative Splicing.International journal of molecular sciences · 2022Review
- How alternative splicing changes the properties of plant proteins.Quantitative plant biology · 2022Review
- The Evolution of Hemocyanin Genes in Caenogastropoda: Gene Duplications and Intron Accumulation in Highly Diverse Gastropods.Journal of molecular evolution · 2021Article
- The Roles of Temperature-Related Post-Transcriptional Regulation in Cereal Floral Development.Plants (Basel, Switzerland) · 2021Review
- Regulation of alternative splicing in response to temperature variation in plants.Journal of experimental botany · 2021Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Plants enter their reproductive phase when the environmental conditions are favourable for the successful production of progeny. The transition from vegetative to reproductive phase is influenced by several environmental factors including ambient temperature. In the model plant Arabidopsis thaliana, SHORT VEGETATIVE PHASE (SVP) is critical for this pathway; svp mutants cannot modify their flowering time in response to ambient temperature. SVP encodes a MADS-box transcription factor that directly represses genes that promote flowering. SVP binds DNA in complexes with other MADS-box transcription factors, including FLOWERING LOCUS M (FLM), which acts with SVP to repress the floral transition at low temperatures. Small temperature changes post-transcriptionally regulate FLM through temperature-dependent alternative splicing (TD-AS). As ambient temperature increases, the predominant FLM splice isoform shifts to encode a protein incapable of exerting a repressive effect on flowering. Here we characterize a closely related MADS-box transcription factor, MADS AFFECTING FLOWERING2 (MAF2), which has independently evolved TD-AS. At low temperatures the most abundant MAF2 splice variant encodes a protein that interacts with SVP to repress flowering. At increased temperature the relative abundance of splice isoforms shifts in favour of an intron-retaining variant that introduces a premature termination codon. We show that this isoform encodes a protein that cannot interact with SVP or repress flowering. At lower temperatures MAF2 and SVP repress flowering in parallel with FLM and SVP, providing an additional input to sense ambient temperature for the control of flowering.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.