ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2014
Analyzing U.S. prescription lists with RxNorm and the ATC/DDD Index.
Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- OntoCodex: a multi-agent biomedical ontology enrichment framework.npj health systems · 2026Article
- Antibiotic Exposure and Cardiovascular Disease Risk: A Nationwide Cohort Study.Journal of the American Heart Association · 2025Article
- Prescription Use and Spending After the Introduction of a Real-Time Prescription Benefit Tool.JAMA network open · 2025Article
- Leveraging Large Language Models for Real-World Data Evidence: A Framework for Automated Treatment Extraction and Data Harmonization.Journal of registry management · 2025Article
- Potential Target Discovery and Drug Repurposing for Coronaviruses: Study Involving a Knowledge Graph-Based Approach.Journal of medical Internet research · 2023Article
- Revealing the dynamic landscape of drug-drug interactions through network analysis.Frontiers in pharmacology · 2023Article
- Developing real-world evidence from real-world data: Transforming raw data into analytical datasets.Learning health systems · 2022Article
- Association between antibiotics use and diabetes incidence in a nationally representative retrospective cohort among Koreans.Scientific reports · 2021Article
- Protocol of a prospective and multicentre China Teratology Birth Cohort (CTBC): association of maternal drug exposure during pregnancy with adverse pregnancy outcomes.BMC pregnancy and childbirth · 2021Article
- Ontological modeling and analysis of experimentally or clinically verified drugs against coronavirus infection.Scientific data · 2021Article
- Optimizing Antihypertensive Medication Classification in Electronic Health Record-Based Data: Classification System Development and Methodological Comparison.JMIR medical informatics · 2020Article
- Comparison of the cohort selection performance of Australian Medicines Terminology to Anatomical Therapeutic Chemical mappings.Journal of the American Medical Informatics Association : JAMIA · 2019Article
- Positioning a Paediatric Compounded Non-Sterile Product Electronic Repository (pCNPeRx) within the Health Information Technology Infrastructure.Pharmacy (Basel, Switzerland) · 2015Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
objectivesTo evaluate the suitability of the ATC/DDD Index (Anatomical Therapeutic Chemical (ATC) Classification System/Defined Daily Dose) for analyzing prescription lists in the U.S.
methodsWe mapped RxNorm clinical drugs to ATC. We used this mapping to classify a large set of prescription drugs with ATC and compared the prescribed daily dose to the defined daily dose (DDD) in ATC.
results64% of the 11,422 clinical drugs could be precisely mapped to ATC. 97% of the 87,001 RxNorm codes from the prescription dataset could be classified with ATC, and 97% of the prescribed daily doses could be assessed.
conclusionsAlthough the mapping of RxNorm ingredients to ATC appears to be largely incomplete, the most frequently prescribed drugs in the prescription dataset we analyzed were covered. This study demonstrates the feasibility of using ATC in conjunction with RxNorm for analyzing U.S. prescription datasets for drug classification and assessment of the prescribed daily doses.
Indexed as
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25954332PMC4419961What OpenQuestion holds
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