Evidence map›Paper›PMID 25954248›Full record

ReviewFrontiers in endocrinology2015

Romosozumab and blosozumab: alternative drugs of mechanical strain-related stimulus toward a cure for osteoporosis.

Toshihiro Sugiyama, Tetsuya Torio, Tsuyoshi Miyajima, Yoon Taek Kim, Hiromi Oda

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Romosozumab does not improve volumetric bone mineral density at distal radius but is associated with early changes in bone strength: a prospective study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. New horizons in treatment of osteoporosis.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2017
    Review
  7. Article
  8. Possible different roles of exercise in preventing vertebral and hip fractures: response to comments by Sugiyama et al.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
    Article
  9. Possible different roles of exercise in preventing vertebral and hip fractures.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
    Article
  10. Exercise for the skeleton in postmenopausal women: fundamental rules of mechanical strain-related stimulus.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
    Article
  11. Both falling and bone fragility should be targeted to prevent hip fracture in older adults.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Toshihiro SugiyamaDepartment of Orthopaedic Surgery, Saitama Medical University , Saitama , Japan.
Tetsuya TorioDepartment of Orthopaedic Surgery, Saitama Medical University , Saitama , Japan.
Tsuyoshi MiyajimaDepartment of Orthopaedic Surgery, Saitama Medical University , Saitama , Japan.
Yoon Taek KimDepartment of Orthopaedic Surgery, Saitama Medical University , Saitama , Japan.
Hiromi OdaDepartment of Orthopaedic Surgery, Saitama Medical University , Saitama , Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

blosozumabmechanostatosteoporosisromosozumabsclerostin

Identifiers

PMID25954248
PMCPMC4404952

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.