Evidence map›Paper›PMID 25954135›Full record

ArticleThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology2015

Improvement Characteristics of Bio-active Materials Coated Fabric on Rat Muscular Mitochondria.

Donghee Lee, Young-Won Kim, Jung-Ha Kim, Misuk Yang, Hyemi Bae, Inja Lim, Hyoweon Bang, Kyung-Chan Go, Gwang-Wung Yang, Yong-Hwan Rho and 3 more

Open access · hybridAbstract read
In one paragraph

Article in The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Trial
  3. CardioprotectionThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2024
    Article
  4. Article
  5. Article
  6. Far-infrared rays enhance mitochondrial biogenesis andThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2021
    Article
  7. Far-infrared radiation stimulates platelet-derived growth factor mediated skeletal muscle cell migration through extracellular matrix-integrin signaling.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Donghee LeeDepartment of Physiology, College of Medicine, Chung-Ang University, Seoul 156-756, Korea.
Young-Won KimDepartment of Physiology, College of Medicine, Chung-Ang University, Seoul 156-756, Korea.
Jung-Ha KimDepartment of Family Medicine, College of Medicine, Chung-Ang University, Seoul 156-756, Korea.
Misuk YangDepartment of Physiology, College of Medicine, Chung-Ang University, Seoul 156-756, Korea.
Hyemi BaeDepartment of Physiology, College of Medicine, Chung-Ang University, Seoul 156-756, Korea.
Inja LimDepartment of Physiology, College of Medicine, Chung-Ang University, Seoul 156-756, Korea.
Hyoweon BangDepartment of Physiology, College of Medicine, Chung-Ang University, Seoul 156-756, Korea.
Kyung-Chan GoResearch and Development Center, VENTEX Co. Ltd., Seoul 138-220, Korea.
Gwang-Wung YangResearch and Development Center, VENTEX Co. Ltd., Seoul 138-220, Korea.
Yong-Hwan RhoResearch and Development Center, VENTEX Co. Ltd., Seoul 138-220, Korea.
Hyo-Suk ParkResearch and Development Center, VENTEX Co. Ltd., Seoul 138-220, Korea.
Eun-Ho ParkResearch and Development Center, VENTEX Co. Ltd., Seoul 138-220, Korea.
Jae-Hong KoDepartment of Physiology, College of Medicine, Chung-Ang University, Seoul 156-756, Korea.
Chung-Ang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study surveys the improvement characteristics in old-aged muscular mitochondria by bio-active materials coated fabric (BMCF). To observe the effects, the fabric (10 and 30%) was worn to old-aged rat then the oxygen consumption efficiency and copy numbers of mitochondria, and mRNA expression of apoptosis- and mitophagy-related genes were verified. By wearing the BMCF, the oxidative respiration significantly increased when using the 30% materials coated fabric. The mitochondrial DNA copy number significantly decreased and subsequently recovered in a dose-dependent manner. The respiratory control ratio to mitochondrial DNA copy number showed a dose-dependent increment. As times passed, Bax, caspase 9, PGC-1α and β-actin increased, and Bcl-2 decreased in a dose-dependent manner. However, the BMCF can be seen to have had no effect on Fas receptor. PINK1 expression did not change considerably and was inclined to decrease in control group, but the expression was down-regulated then subsequently increased with the use of the BMCF in a dose-dependent manner. Caspase 3 increased and subsequently decreased in a dose-dependent manner. These results suggest that the BMCF invigorates mitophagy and improves mitochondrial oxidative respiration in skeletal muscle, and in early stage of apoptosis induced by the BMCF is not related to extrinsic death-receptor mediated but mitochondria-mediated signaling pathway.

Indexed as

ApoptosisBio-active materials coated fabricMitochondriaMitophagyOxidative respiration

Identifiers

PMID25954135
PMCPMC4422970
OpenAlexW1749285628

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.