ArticleThe Journal of infectious diseases2015
High Oral Human Papillomavirus Type 16 Load Predicts Long-term Persistence in Individuals With or at Risk for HIV Infection.
Article in The Journal of infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- Oral HPV16 DNA as a screening tool to detect early oropharyngeal squamous cell carcinoma.Cancer science · 2020Article
- Quantitative Oral HPV16 and HPV18 Detection in Persons Attending Dental Clinics.Sexually transmitted diseases · 2020Article
- Evaluating the Utility and Prevalence of HPV Biomarkers in Oral Rinses and Serology for HPV-related Oropharyngeal Cancer.Cancer prevention research (Philadelphia, Pa.) · 2019Article
- Development and interlaboratory agreement of real-time PCR for HPV16 quantification in liquid-based cervical samples.Papillomavirus research (Amsterdam, Netherlands) · 2018Article
- HPV-16 in a distinct subset of oral epithelial dysplasia.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2017Article
- Current and Emerging Molecular Tests for Human Papillomavirus-Related Neoplasia in the Genomic Era.The Journal of molecular diagnostics : JMD · 2017Review
- The potential impact of prophylactic human papillomavirus vaccination on oropharyngeal cancer.Cancer · 2016Review
- Partner Human Papillomavirus Viral Load and Incident Human Papillomavirus Detection in Heterosexual Couples.The Journal of infectious diseases · 2016Article
- Concordance of oral HPV prevalence between patients with oropharyngeal cancer and their partners.Infectious agents and cancer · 2016Article
Corrections and comments
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Authors and funding
15 authors at 10 institutions in 2 countries.
Funding
Abstract
The association between oral human papillomavirus 16 (HPV16) DNA load and infection clearance was evaluated among 88 individuals with oral HPV16 infection who were identified within a prospective cohort of 1470 HIV-infected and uninfected individuals. Oral rinse specimens were collected semiannually for up to 5 years. The oral HPV16 load at the time of the first positive test result was significantly associated with the time to clearance of infection (continuous P trends <.01). Notably, clearance rates by 24 months were 41% and 94% in the highest and lowest HPV16 load tertiles (P = .03), respectively. High oral HPV16 load warrants consideration as a biomarker for infection persistence, the presumed precursor of HPV16-associated oropharyngeal cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.