Evidence map›Paper›PMID 25953919›Full record

ArticleCirculation research2015

Novel mechanism of transient outward potassium channel current regulation in the heart: implications for cardiac electrophysiology in health and disease.

Michael S Bohnen, Vivek Iyer, Kevin J Sampson, Robert S Kass

Abstract readEditorialComment
In one paragraph

Article in Circulation research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Human atrial fibrillation and genetic defects in transient outward currents: mechanistic insights from multi-scale computational models.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Michael S BohnenFrom the Department of Pharmacology (M.S.B., K.J.S., R.S.K.), and Department of Medicine (V.I.), College of Physicians & Surgeons, Columbia University, NY.
Vivek IyerFrom the Department of Pharmacology (M.S.B., K.J.S., R.S.K.), and Department of Medicine (V.I.), College of Physicians & Surgeons, Columbia University, NY.
Kevin J SampsonFrom the Department of Pharmacology (M.S.B., K.J.S., R.S.K.), and Department of Medicine (V.I.), College of Physicians & Surgeons, Columbia University, NY.
Robert S KassFrom the Department of Pharmacology (M.S.B., K.J.S., R.S.K.), and Department of Medicine (V.I.), College of Physicians & Surgeons, Columbia University, NY. rsk20@cumc.columbia.edu.

Funding

Modulation of KCNQ1 channel activityR01GM109762 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI KASS, ROBERT S, LARSSON, HANS PETER · 2014 to 2022
$3.1M
Cell-type Specificity of Heritable Channelopathies: Role of the Purkinje FiberK08HL116790 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI IYER, VIVEK · 2013 to 2017
$728k
NHLBI NIH HHS K08 HL116790NIGMS NIH HHS 5R01 GM109762-02NIGMS NIH HHS R01 GM109762
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCold Shock Proteins and PeptidesMyocytes, CardiacRNA-Binding ProteinsShal Potassium ChannelsCold Shock Proteins and PeptidesRNA-Binding ProteinsShal Potassium Channelsarrhythmiacold-inducible RNA-binding proteinEditorial

Identifiers

PMID25953919
PMCPMC4428686

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.