Evidence map›Paper›PMID 25953199›Full record

ArticleJournal of the American Geriatrics Society2015

Smoking, central adiposity, and poor glycemic control increase risk of hearing impairment.

Karen J Cruickshanks, David M Nondahl, Dayna S Dalton, Mary E Fischer, Barbara E K Klein, Ronald Klein, F Javier Nieto, Carla R Schubert, Ted S Tweed

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 2 pooled it
7.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 2 syntheses or guidelines pooled it, 168 citations in OpenAlex.

  1. Vascular mechanisms in acute unilateral peripheral vestibulopathy: a systematic review.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2021
    Pooled it
  2. Pooled it
  3. Does occupational noise exposure aggravate age-related hearing loss? A population-based study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  4. Genotype-guided Recall Delineates the Adult Auditory Phenotype in GJB2 p.V37I Homozygotes: High-frequency Vulnerability and Environmental Modulation.Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2026
    Article
  5. Observational
  6. Review
  7. [An interpretation of the blue book: the report on hearing health in china (2025)].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026
    Article
  8. Article
  9. Self-Reported Type 2 Diabetes and the Rate of Hearing Decline in Aging.Journal of speech, language, and hearing research : JSLHR · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Noise Exposure History and Age-Related Changes to Hearing.JAMA otolaryngology-- head & neck surgery · 2025
    Article
  17. Article
  18. Hearing Care Within Diabetes Care: Strategies for Direct Inclusion.Clinical diabetes : a publication of the American Diabetes Association · 2025
    Article
  19. Article
  20. Article

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Karen J CruickshanksDepartment of Ophthalmology and Visual Sciences, University of Wisconsin at Madison, Madison, Wisconsin.
David M NondahlDepartment of Ophthalmology and Visual Sciences, University of Wisconsin at Madison, Madison, Wisconsin.
Dayna S DaltonDepartment of Ophthalmology and Visual Sciences, University of Wisconsin at Madison, Madison, Wisconsin.
Mary E FischerDepartment of Ophthalmology and Visual Sciences, University of Wisconsin at Madison, Madison, Wisconsin.
Barbara E K KleinDepartment of Ophthalmology and Visual Sciences, University of Wisconsin at Madison, Madison, Wisconsin.
Ronald KleinDepartment of Ophthalmology and Visual Sciences, University of Wisconsin at Madison, Madison, Wisconsin.
F Javier NietoDepartment of Population Health Sciences, University of Wisconsin at Madison, Madison, Wisconsin.
Carla R SchubertDepartment of Ophthalmology and Visual Sciences, University of Wisconsin at Madison, Madison, Wisconsin.
Ted S TweedDepartment of Ophthalmology and Visual Sciences, University of Wisconsin at Madison, Madison, Wisconsin.
University of Wisconsin–Madison · USUniversity of Wisconsin Health · US

Funding

THE EPIDEMIOLOGY OF AGE-RELATED OCULAR DISEASEU10EY006594 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI KLEIN, BARBARA EDEN · 1987 to 2018
$17.3M
Epidemiology of Age-related Hearing LossR37AG011099 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI CRUICKSHANKS, KAREN J · 2009 to 2018
$7.4M
NEI NIH HHS U10 EY006594NEI NIH HHS U10EY06594NIA NIH HHS R37 AG011099NIA NIH HHS R37AG011099
6 · The paper itself

Abstract

objectivesTo determine associations between smoking, adiposity, diabetes mellitus, and other risk factors for cardiovascular disease (CVD) and the 15-year incidence of hearing impairment (HI).

designA longitudinal population-based cohort study (1993-95 to 2009-10), the Epidemiology of Hearing Loss Study (EHLS).

settingBeaver Dam, Wisconsin.

participantsParticipants in the Beaver Dam Eye Study (1988-90; residents of Beaver Dam, WI, aged 43-84 in 1987-88) were eligible for the EHLS. There were 1,925 participants with normal hearing at baseline. MEASUREMENTS: Fifteen-year cumulative incidence of HI (pure-tone average of hearing thresholds at 0.5, 1, 2, and 4 kHz greater than 25 decibels hearing level in either ear). Cigarette smoking, exercise, and other factors were ascertained according to questionnaire. Blood pressure, waist circumference, body mass index, and glycosylated hemoglobin were measured.

resultsFollow-up examinations (≥1) were obtained from 87.2% (n=1,678; mean baseline age 61). The 15-year cumulative incidence of HI was 56.8%. Adjusting for age and sex, current smoking (hazard ratio (HR)=1.31, P=.048), education (<16 years; HR=1.35, P=.01), waist circumference (HR=1.08 per 10 cm, P=.02), and poorly controlled diabetes mellitus (HR=2.03, P=.048) were associated with greater risk of HI. Former smokers and people with better-controlled diabetes mellitus were not at greater risk.

conclusionSmoking, central adiposity, and poorly controlled diabetes mellitus predicted incident HI. These well-known risk factors for CVD suggest that vascular changes may contribute to HI in aging. Interventions targeting reductions in smoking and adiposity and better glycemic control in people with diabetes mellitus may help prevent or delay the onset of HI.

Indexed as

AgedAged, 80 and overBlood GlucoseCohort StudiesDiabetes ComplicationsDiabetes MellitusFemaleHearing LossHumansIncidenceMaleMiddle AgedObesity, AbdominalRisk FactorsSmokingWisconsinBlood Glucoseadipositydiabetes mellituspresbycusisrisk factorssmoking

Identifiers

PMID25953199
PMCPMC4439261
OpenAlexW1717409423

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.