ArticleEye (London, England)2015
Correlation of structure and function of the macula in patients with retinitis pigmentosa.
Article in Eye (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed.
- Visual Field Estimation in X-Linked Retinitis Pigmentosa Associated with Retinitis Pigmentosa GTPase Regulator (Ophthalmology science · 2026Article
- Unifying Structure and Function Towards a Comprehensive Macular Evaluation in Eye Disorders: A Multi-Modal Approach Using Microperimetry and Optical Coherence Tomography.IEEE transactions on bio-medical engineering · 2025Article
- Does microperimetry have a role in monitoring visual function in patients with Behçet uveitis?BMC ophthalmology · 2024Observational
- RPE65 c.353G>A, p.(Arg118Lys): A Novel Point Mutation Associated with Retinitis Pigmentosa and Macular AtrophyInternational journal of molecular sciences · 2022Article
- Measurement of macular thickness with optical coherence tomography: impact of using a paediatric reference database and analysis of interocular symmetry.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021Article
- The Impact of Cataract Surgery on Contrast Visual Acuity and Retinal Sensitivity in Patients with Retinitis Pigmentosa.Journal of ophthalmology · 2021Article
- Biomarkers in Usher syndrome: ultra-widefield fundus autofluorescence and optical coherence tomography findings and their correlation with visual acuity and electrophysiology findings.Documenta ophthalmologica. Advances in ophthalmology · 2020Article
- Optical coherence tomography in the evaluation of retinitis pigmentosa.Ophthalmic genetics · 2020Review
- Edge of Scotoma Sensitivity as a Microperimetry Clinical Trial End Point inTranslational vision science & technology · 2020Article
- Interpreting MAIA Microperimetry Using Age- and Retinal Loci-Specific Reference Thresholds.Translational vision science & technology · 2020Article
- The qualitative assessment of optical coherence tomography and the central retinal sensitivity in patients with retinitis pigmentosa.PloS one · 2020Observational
- The association between cone density and visual function in the macula of patients with retinitis pigmentosa.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019Article
- Cone Spacing Correlates With Retinal Thickness and Microperimetry in Patients With Inherited Retinal Degenerations.Investigative ophthalmology & visual science · 2019Article
- Dysflective Cones.Advances in experimental medicine and biology · 2019Review
- Circumpapillary microperimetry to detect glaucoma: a pilot study for sector-based comparison to circumpapillary retinal nerve fiber layer measurement.International ophthalmology · 2019Article
- Optimising the Structure-Function Relationship at the Locus of Deficit in Retinal Disease.Frontiers in neuroscience · 2019Article
- Quantifying microstructural changes in retinitis pigmentosa using spectral domain - optical coherence tomography.Eye and vision (London, England) · 2019Article
- Determination of Length of Interdigitation Zone by Optical Coherence Tomography and Retinal Sensitivity by Microperimetry and Their Relationship to Progression of Retinitis Pigmentosa.BioMed research international · 2019Article
- Optical Coherence Tomography of Animal Models of Retinitis Pigmentosa: From Animal Studies to Clinical Applications.BioMed research international · 2019Review
- Assessment of Central Visual Function in Patients with Retinitis Pigmentosa.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo correlate the structure of the macula, as measured by spectral-domain optical coherence tomography (SD-OCT) and function, as measured by microperimetry (MAIA) in patients with retinitis pigmentosa (RP) and relatively good visual acuity.
designProspective, cross-sectional, non-intervention study. SUBJECTS: Patients with RP.
methodsThirty patients with RP and good central visual acuity were identified. Each patient underwent SD-OCT of the macula and microperimetry. The images were overlaid using the custom-designed software. The retinal sensitivity by microperimetry was correlated with corresponding retinal thickness, as measured by the SD-OCT. ELM, COST, and IS/OS junction were scored as intact, disrupted, or absent.
main outcome measuresComparing the retinal sensitivity on the MAIA with various measurements on the SD-OCT.
resultsThe retinal sensitivity on the MAIA showed a significant correlation with total retinal thickness and outer retinal thickness on the SD-OCT. There was no association with either the inner retinal thickness or the choroidal thickness. ORT showed a statistically significant correlation with the anatomical classification of ELM (r=-0.76, P<0.001), IS/OS (r=-0.800, P<0.001), and COST (r=-0.733, P<0.001).
conclusionThis study determined that there was a high correlation of the structure and function of the central macula in patients with RP. These studies are important to establish surrogate markers that can be used as end points for various tests in future therapeutic clinical trials.
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