ArticleBMC pulmonary medicine2015
Relationship between daily physical activity and aerobic fitness in adults with cystic fibrosis.
Article in BMC pulmonary medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- The 2025 European Cystic Fibrosis Society position statement on physical activity assessment in cystic fibrosis.European respiratory review : an official journal of the European Respiratory Society · 2025Guideline
- Mediating effects of physical activity enjoyment on physical activity levels in adults with cystic fibrosis.Frontiers in sports and active living · 2026Article
- Longitudinal changes in habitual physical activity in adult people with cystic fibrosis in the presence or absence of treatment with elexacaftor/tezacaftor/ivacaftor.Frontiers in sports and active living · 2024Article
- Physical activity and its correlates in people with cystic fibrosis: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2022Review
- A Compositional Analysis of Physical Activity, Sedentary Time, and Sleep and Associated Health Outcomes in Children and Adults with Cystic Fibrosis.International journal of environmental research and public health · 2022Article
- Ventilatory efficiency and its clinical and prognostic value in adults with cystic fibrosis.European respiratory review : an official journal of the European Respiratory Society · 2021Review
- Association between habitual physical activity (HPA) and sleep quality in patients with cystic fibrosis.Sleep & breathing = Schlaf & Atmung · 2021Article
- Factors influencing physical activity in adults with cystic fibrosis.BMC pulmonary medicine · 2021Article
- Association between Estimated Cardiorespiratory Fitness and Depression among Middle-income Country Adults: Evidence from National Health Survey.Clinical practice and epidemiology in mental health : CP & EMH · 2021Article
- Do accelerometer-based physical activity patterns differentially affect cardiorespiratory fitness? A growth mixture modeling approach.Journal of behavioral medicine · 2020Article
- Reduced exertion high-intensity interval training (REHIT) in an adult with Cystic Fibrosis: A mixed-methods case study.Respiratory medicine case reports · 2020Article
- Article
- Assessing performance in pre-season wrestling athletes using biomarkers.Biochemia medica · 2018Observational
- Exercise oxidative skeletal muscle metabolism in adolescents with cystic fibrosis.Experimental physiology · 2016Article
- The PAY test: a new approach for assessing functional performance in children and adolescents with asthma.Jornal de pediatriaArticle
- Physiological predictors of cardiorespiratory fitness in children and adolescents with cystic fibrosis without ventilatory limitation.Therapeutic advances in respiratory diseaseArticle
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe best clinical practice to investigate aerobic fitness includes measurements obtained during cardiopulmonary exercise testing (CPET), however it remains an underutilised clinical measure in cystic fibrosis (CF). To investigate this further, different methods of quantifying exercise capacity in CF are required. The possibility that measuring physical activity (PA) by a portable accelerometer could be used to assess the CF aerobic state and could be added among the CPET surrogates has not been investigated. The aim of this study was to examine the relationship between PA and exercise fitness both at submaximal and maximal levels in clinically stable adults with CF.
methodsThirty CF patients (FEV1 71 ± 19% predicted) and fifteen healthy controls undertook an incremental CPET on a cycle ergometer. CPET-related measurements included: oxygen uptake (V'O2), carbon dioxide production (V'CO2), ventilatory profile, heart rate (HR) and oxygen pulse (V'O2/HR) throughout exercise and at lactic threshold (LT) and peak. LT measures represent submaximal exercise related data. PA was assessed using the accelerometer SenseWear Pro3 Armband.
resultsModerate (>4.8 metabolic equivalents (METS)) and moderate + vigorous (>7.2 METS) PA was related to V'O2 (p = 0.005 and p = 0.009, respectively) and work rate (p = 0.004 and p = 0.002, respectively) at LT. Moderate PA or greater was positively related to peak V'O2 (p = 0.005 and p = 0.003, respectively). Daily PA levels were similar in CF and healthy controls. Except for peak values, V'O2 profile and the V'O2 at LT were comparable between CF and healthy controls.
conclusionsIn adult CF patients daily PA positively correlated with aerobic capacity. PA measurements are a valuable tool in the assessment of exercise performance in an adult CF population and could be used for interventional exercise trials to optimize exercise performance and health status. PA levels and parameters obtained at submaximal exercise are similar in CF and in healthy controls.
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