Evidence map›Paper›PMID 25952743›Full record

Trial reportMedical decision making : an international journal of the Society for Medical Decision Making2015

Presenting Numeric Information with Percentages and Descriptive Risk Labels: A Randomized Trial.

Aleksandr Sinayev, Ellen Peters, Martin Tusler, Liana Fraenkel

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Medical decision making : an international journal of the Society for Medical Decision Making, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Improving cancer clinical trial enrollment and patient understanding using TrialTalk, a structured communication method: a pilot randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Trial
  2. Trial
  3. Trial
  4. Trial
  5. Article
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  7. Article
  8. Review
  9. Investigation of Platelet Function Analyzer 200 platelet function measurements in healthy cats and cats receiving clopidogrel.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2023
    Article
  10. Review
  11. Article
  12. Article
  13. Practising shared decision making in primary care.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2021
    Article
  14. Evaluation of adverse drug reaction formatting in drug information databases.Journal of the Medical Library Association : JMLA · 2020
    Article
  15. Article
  16. Article
  17. Use of descriptive and experiential information in decision making by young and older adults.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2018
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aleksandr SinayevOhio State University, Columbus, OH (AS, EP, MT)
Ellen PetersOhio State University, Columbus, OH (AS, EP, MT)
Martin TuslerOhio State University, Columbus, OH (AS, EP, MT)
Liana FraenkelYale School of Medicine, New Haven, CT (LF).

Funding

Internet Interviewing and the HRSR01AG020717 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KAPTEYN, ARIE · 2002 to 2015
$18.8M
Roybal Center for Health Decision Making and Financial Independence in Old AgeP30AG024962 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KAPTEYN, ARIE · 2004 to 2018
$5.5M
Improving Decision Making in Patients with Rheumatic DiseaseK24AR060231 · NIAMS · YALE UNIVERSITY · PI FRAENKEL, LIANA · 2011 to 2018
$1.2M
NIAMS NIH HHS AR060231-01NIAMS NIH HHS K24 AR060231NIA NIH HHS P30 AG024962NIA NIH HHS R01 AG020717NIA NIH HHS R01AG20717
6 · The paper itself

Abstract

backgroundPrevious research demonstrated that providing (v. not providing) numeric information about the adverse effects (AEs) of medications increased comprehension and willingness to use medication but left open the question about which numeric format is best. The objective was to determine which of 4 tested formats (percentage, frequency, percentage + risk label, frequency + risk label) maximizes comprehension and willingness to use medication across age and numeracy levels.

methodsIn a cross-sectional internet survey (N = 368; American Life Panel, 15 May 2008 to 18 June 2008), respondents were presented with a hypothetical prescription medication for high cholesterol. AE likelihoods were described using 1 of 4 tested formats. Main outcome measures were risk comprehension (ability to identify AE likelihood from a table) and willingness to use the medication (7-point scale; not likely = 0, very likely = 6).

resultsThe percentage + risk label format resulted in the highest comprehension and willingness to use the medication compared with the other 3 formats (mean comprehension in percentage + risk label format = 95% v. mean across the other 3 formats = 81%; mean willingness = 3.3 v. 2.95, respectively). Comprehension differences between percentage and frequency formats were smaller among the less numerate. Willingness to use medication depended less on age and numeracy when labels were used. Generalizability is limited by the use of a sample that was older, more educated, and better off financially than national averages.

conclusionsProviding numeric AE-likelihood information in a percentage format with risk labels is likely to increase risk comprehension and willingness to use a medication compared with other numeric formats.

Indexed as

Decision MakingDrug-Related Side Effects and Adverse ReactionsHealth Knowledge, Attitudes, PracticePatient Medication KnowledgeAdolescentAdultAgedAged, 80 and overAge DistributionCommunicationComprehensionDrug LabelingFemaleHumansHypercholesterolemiaInternetPrescription Drugsadherenceaginginformed decision makingnumeracypharmaceutical decision makingrisk communicationrisk comprehensionstatins

Identifiers

PMID25952743
PMCPMC4592369

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.