Evidence map›Paper›PMID 25952669›Full record

ArticleCell research2015

In-cell infection: bringing uninvited guests.

Yongchan Lee, Michael Overholtzer

Abstract readComment
In one paragraph

Article in Cell research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Revisiting Regulated Cell Death Responses in Viral Infections.International journal of molecular sciences · 2022
    Review
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Yongchan LeeCell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Michael OverholtzerCell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell-in-cell structures resulting from live cell engulfment were identified more than 100 years ago, but their physiological significance has remained largely obscure. Now Ni et al. identify a new role for cell-in-cell structure formation, called "in-cell infection" that spreads Epstein-Barr virus from infected B cells to epithelial cells, an activity that may predispose to cancer.

Indexed as

B-LymphocytesEpithelial CellsEpstein-Barr Virus InfectionsHumansNasopharyngeal Neoplasms

Identifiers

PMID25952669
PMCPMC4456624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.