Evidence map›Paper›PMID 25952160›Full record

Trial reportThe international journal of behavioral nutrition and physical activity2015

Improving dietary quality in youth with type 1 diabetes: randomized clinical trial of a family-based behavioral intervention.

Tonja R Nansel, Lori M B Laffel, Denise L Haynie, Sanjeev N Mehta, Leah M Lipsky, Lisa K Volkening, Deborah A Butler, Laurie A Higgins, Aiyi Liu

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The international journal of behavioral nutrition and physical activity, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00999375 (Cultivating Healthy Environments in Families With Type 1 Diabetes), which is not on this map. Cited by 43 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00999375 phase2completednot on this map

Cultivating Healthy Environments in Families With Type 1 Diabetes (CHEF)

TypeinterventionalSponsorEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Ran2009 to 2013Enrolled293ConditionsType I DiabetesArmsEducation, Problem Solving, Social Learning, Behavior Modification
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  18. I Should but I Can't: Controlled Motivation and Self-Efficacy Are Related to Disordered Eating Behaviors in Adolescents With Type 1 Diabetes.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tonja R NanselHealth Behavior Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, 6100 Executive Blvd. Rm 7B13R, MSC 7510, Bethesda, MD, USA. nanselt@mail.nih.gov.
Lori M B LaffelPediatric, Adolescent, and Young Adult Section, Genetics and Epidemiology Section, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA. lori.laffel@joslin.harvard.edu.
Denise L HaynieHealth Behavior Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, 6100 Executive Blvd. Rm 7B13R, MSC 7510, Bethesda, MD, USA. haynied@mail.nih.gov.
Sanjeev N MehtaPediatric, Adolescent, and Young Adult Section, Genetics and Epidemiology Section, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA. sanjeev.mehta@joslin.harvard.edu.
Leah M LipskyHealth Behavior Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, 6100 Executive Blvd. Rm 7B13R, MSC 7510, Bethesda, MD, USA. lipskylm@mail.nih.gov.
Lisa K VolkeningPediatric, Adolescent, and Young Adult Section, Genetics and Epidemiology Section, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA. lisa.volkening@joslin.harvard.edu.
Deborah A ButlerPediatric, Adolescent, and Young Adult Section, Genetics and Epidemiology Section, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA. deborah.butler@joslin.harvard.edu.
Laurie A HigginsPediatric, Adolescent, and Young Adult Section, Genetics and Epidemiology Section, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA. laurie.higgins@joslin.harvard.edu.
Aiyi LiuHealth Behavior Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, 6100 Executive Blvd. Rm 7B13R, MSC 7510, Bethesda, MD, USA. liua@mail.nih.gov.

Funding

SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI ROHIT N. KULKARNI · 1986 to 2026
$50.5M
Enhancing Carbohydrate Quality in Diabetes ManagementZIAHD008805 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI NANSEL, TONJA · 2009 to 2022
$4.4M
Statistical Methods for Evaluation of BiomarkersZIAHD008875 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI LIU, AIYI · 2009 to 2025
$3.8M
Intramural NIH HHSNICHD NIH HHS HHSN267200703434CNIDDK NIH HHS P30 DK036836NIDDK NIH HHS P30DK036836PHS HHS HHSN267200703434CPHS HHS HHSN2752008000031/HHSN275002
6 · The paper itself

Abstract

backgroundDiets of children with type 1 diabetes are low in fruits, vegetables, and whole grains, and high in foods of minimal nutritional value, increasing risk for future adverse health outcomes. This 18-month randomized clinical trial tested the effect of a family-based behavioral intervention integrating motivational interviewing, active learning, and applied problem-solving on the primary outcomes of dietary intake and glycemic control among youth with type 1 diabetes.

methodsA parallel-group study with equal randomization was conducted at an outpatient, free-standing, multidisciplinary tertiary diabetes center in the United States. Eligible youth were those age 8-16 years with type 1 diabetes diagnosis ≥1 year and hemoglobin A1c (HbA1c) ≥6.5% and ≤10.0%. Participants were 136 parent-youth dyads (treatment n = 66, control n = 70). The intervention consisted of 9 in-clinic sessions delivered to the child and parent; control condition comprised equivalent assessments and number of contacts without dietary advice. Dietary intake was assessed using 3-day diet records at 6 time points across the 18-month study. Dietary outcomes included the Healthy Eating Index-2005 (HEI2005; index measuring conformance to the 2005 United States Dietary Guidelines for Americans) and Whole Plant Food Density (WPFD; number of cup or ounce equivalents per 1000 kcal of whole grains, whole fruit, vegetables, legumes, nuts, and seeds consumed). HbA1c was obtained every 3 months. Overall comparison of outcome variables between intervention and usual care groups was conducted using permutation tests.

resultsThere was a positive intervention effect across the study duration for HEI2005 (p = .015) and WPFD (p = .004). At 18 months, HEI2005 was 7.2 greater (mean ± SE 64.6 ± 2.0 versus 57.4 ± 1.6), and WPFD was 0.5 greater (2.2 ± 0.1 versus 1.7 ± 0.1) in the intervention group versus control. There was no difference between groups in HbA1c across the study duration.

conclusionsThis behavioral nutrition intervention improved dietary quality among youth with type 1 diabetes, but did not impact glycemic control. Findings indicate the potential utility of incorporating such strategies into clinical care, and suggest that improvement in diet quality can be achieved in families living with this burdensome disease.

trial registrationClinicaltrials.gov registration number: NCT00999375.

Indexed as

FamilyNutrition PolicyAdolescentBehavior TherapyBlood GlucoseChildDiabetes Mellitus, Type 1DietDiet RecordsFemaleGlycated HemoglobinHumansMaleTreatment OutcomeBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, human

Identifiers

PMID25952160
PMCPMC4436744

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.