ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2016
Retinal vessel oxygen saturation and vessel diameter in retinitis pigmentosa at various ages.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 40 citations in OpenAlex.
- Retinal Oximetry in a Healthy Japanese Population.PloS one · 2016Trial
- A comparison of retinal vascular oxygen saturation between myopic children and adults.BMC ophthalmology · 2026Observational
- Retinal oximetry: new insights into ocular and systemic diseases.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Review
- Non-Invasive Metabolic and Structural Retinal Markers in Patients with Giant Cell Arteritis and Polymyalgia Rheumatica: A Cross-Sectional Study.Metabolites · 2022Article
- The influence of retinal oxygen saturation and choroidal volume on postoperative outcomes in patients with epiretinal membrane.Acta ophthalmologica · 2022Article
- The retinal vasculature pathophysiological changes in vision recovery after treatment for indirect traumatic optic neuropathy patients.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021Article
- Advances in Retinal Oximetry.Translational vision science & technology · 2021Review
- In depth understanding of retinitis pigmentosa pathogenesis through optical coherence tomography angiography analysis: a narrative review.International journal of ophthalmology · 2021Review
- Retinal Vessel Oxygen Saturation Measurement Protocols and Their Agreement.Translational vision science & technology · 2020Article
- Oxidative Stress, a Crossroad Between Rare Diseases and Neurodegeneration.Antioxidants (Basel, Switzerland) · 2020Review
- Quantification of Macular Microvascular Changes in Retinitis Pigmentosa Using Optical Coherence Tomography Angiography.Clinical ophthalmology (Auckland, N.Z.) · 2020Article
- Metabolic monitoring of transcorneal electrical stimulation in retinitis pigmentosa.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020Observational
- Analysis of Foveal and Parafoveal Microvascular Density and Retinal Vessel Caliber Alteration in Inactive Graves' Ophthalmopathy.Journal of ophthalmology · 2020Article
- Higher retinal vessel oxygen saturation: investigating its relationship with macular oedema in retinitis pigmentosa patients.Eye (London, England) · 2018Article
- High-resolution Imaging in Male Germ Cell-Associated Kinase (MAK)-related Retinal Degeneration.American journal of ophthalmology · 2018Article
- Development and Validation of Non simultaneous Retinal Image Acquisition-Based Retinal Oximeter.Scientific reports · 2017Article
- Macular Retinal Vessel Oxygen Saturation Elevation in Chinese Central Serous Chorioretinopathy.Journal of ophthalmology · 2017Article
- Small Molecular-Sized Artesunate Attenuates Ocular Neovascularization via VEGFR2, PKCα, and PDGFR Targets.Scientific reports · 2016Article
- Shifts in retinal vessel diameter and oxygen saturation in Chinese type 2 diabetes mellitus patients.BMC ophthalmology · 2016Article
- Hyperspectral Image Mapping Spectrometry for Retinal Oximetry Measurements in Four Diseased Eyes.International ophthalmology clinics · 2016Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study was conducted to determine whether oxygen saturation and retinal blood vessel diameter are affected by retinitis pigmentosa (RP) at various ages.
methodsRelative oxygen saturation was measured in retinal blood vessels in 68 RP patients and 136 normal subjects using the Oxymap T1 retinal oximeter. Subjects were divided into two age groups: Group A (20-40 years) and Group B (> 40 years). One randomly selected eye of each subject was used for statistical analysis. Student's t tests were used to analyze the mean saturation and diameter of retinal arterioles and venules and arteriovenous differences between RP and normal subjects in the two age groups. A Spearman test was used to analyze the correlation of mean saturation of retinal arterioles (AS) and arteriovenous differences (AVS) with visual acuity, disease duration, and electroretinogram (ERG) b-wave amplitude in patients with RP.
resultsAS was significantly higher in patients with RP (105.5 ± 9.4 %) than in normal subjects (94.5 ± 4.4 %, p = 0.000) in Group A, while in Group B, AS was significantly lower in RP patients (86.8 ± 10.3 %) than in healthy subjects (96.0 ± 4.8 %, p = 0.000). Vessel diameter was smaller in RP patients than in normal subjects. AS and AVS showed a negative correlation with disease duration and a tendency toward positive correlation with ERG b-wave in patients with RP.
conclusionsThe shifting characteristics of retinal vessel oxygen saturation suggest that the pathological mechanism of retinal oxygen metabolic disorder differs by age in patients with RP.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.