Trial reportEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2016
Psychological stress and its relationship with persistent allergic rhinitis.
Trial report in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 26 citations in OpenAlex.
- Philippine Clinical Practice Guidelines for Periodic Health Examination: Screening for Mental Health and Addiction.Acta medica Philippina · 2026Article
- Rhinitis medicomentosa and substance addiction.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Article
- Allergic Sensitization and Psychosomatic Involvement in Outdoor and Indoor Workers: A Preliminary and Explorative Survey of Motorway Toll Collectors and Office Employees.Healthcare (Basel, Switzerland) · 2024Article
- Quantitative assessment and correlational analysis of subjective and objective indicators in patients with allergic rhinitis.Asia Pacific allergy · 2024Article
- No causal association between allergic rhinitis and migraine: a Mendelian randomization study.European journal of medical research · 2024Article
- Article
- The Psychological Relieving Effect of Drug Provocation Test in Drug Hypersensitivity.Journal of asthma and allergy · 2022Article
- Association between Perceived Stress and Rhinitis-Related Quality of Life: A Multicenter, Cross-Sectional Study.Journal of clinical medicine · 2021Article
- Stress and Nasal Allergy: Corticotropin-Releasing Hormone Stimulates Mast Cell Degranulation and Proliferation in Human Nasal Mucosa.International journal of molecular sciences · 2021Article
- Effects of a probiotic treatment (BMJ open · 2019Article
- Article
- Burden of allergic respiratory disease: a systematic review.Clinical and molecular allergy : CMA · 2016Review
- Impact of Obstructive Sleep Apnea on Outcomes of Minimally Invasive Nasal Surgery for Chronic Rhinitis.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-facialeArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledAllergic rhinitis is considered to be a major health problem that impairs quality of life. A possible relationship with psychological stress may exist. The aim of this study is to verify the relationship between persistent allergic rhinitis (PAR) and psychological stress aiming to improve treatment and thereby quality of life (QOL) of patients. Patients with PAR (166) were diagnosed then analyzed using the Kessler Psychological Distress Scale. Patients with allergic rhinitis and who were positive on the Kessler scale (122) were randomly divided equally into a control group which received levocetirizine and a study group which received levocetirizine and imipramine. Nasal symptom assessment and QOL assessment were performed in all patients after treatment. Of the 166 patients with PAR, 122 (73.5 %) were positive on the Kessler Psychological Distress Scale. There was a marked improvement in the study group compared with the control group as regards nasal symptoms with better QOL in the study group (6.93) compared with the control group (2.13). Psychological stress has a strong impact on persistent allergic rhinitis. When stress is controlled by a combined treatment of imipramine and levocetirizine, allergic rhinitis symptoms improved and a better QOL was obtained. LEVEL OF EVIDENCE: 3b.
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