SynthesisSeminars in oncology nursing2015
Genetic tests to identify risk for breast cancer.
Synthesis in Seminars in oncology nursing, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Racial and ethnic differences in knowledge and attitudes about genetic testing in the US: Systematic review.Journal of genetic counseling · 2019Pooled it
- Article
- Pan-cancer Analysis Combined with Experiments Deciphers PHB Regulation for Breast Cancer Cell Survival and Predicts Biomarker Function.Combinatorial chemistry & high throughput screening · 2024Article
- Challenges and Innovations in Breast Cancer Screening in India: A Review of Epidemiological Trends and Diagnostic Strategies.International journal of breast cancer · 2024Review
- Encapsulation and adhesion of nanoparticles as a potential biomarker for TNBC cells metastatic propensity.Scientific reports · 2023Article
- Proteomic Markers for Mechanobiological Properties of Metastatic Cancer Cells.International journal of molecular sciences · 2023Review
- Genotypes and Haplotypes in theBritish journal of biomedical science · 2022Article
- Feasibility of genetic testing for cancer risk assessment programme in Nigeria.Ecancermedicalscience · 2021Article
- Genomics-Guided Immunotherapy for Precision Medicine in Cancer.Cancer biotherapy & radiopharmaceuticals · 2019Review
- Functional coding and non-coding variants in human BRCA1 gene and their use in genetic screening.Medical oncology (Northwood, London, England) · 2019Review
- Racial/Ethnic Disparities in BRCA Counseling and Testing: a Narrative Review.Journal of racial and ethnic health disparities · 2019Review
- Development of a Web-based Family Intervention for BRCA Carriers and Their Biological Relatives: Acceptability, Feasibility, and Usability Study.JMIR cancer · 2018Article
- Cancer Predisposition Cascade Screening for Hereditary Breast/Ovarian Cancer and Lynch Syndromes in Switzerland: Study Protocol.JMIR research protocols · 2017Article
- Natural variation of macrophage activation as disease-relevant phenotype predictive of inflammation and cancer survival.Nature communications · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
objectivesTo describe the currently available genetic tests that identify hereditary risk for breast cancer. DATA SOURCES: Systematic review of scientific literature, clinical practice guidelines, and data published by test manufacturers.
conclusionChanges in gene patent laws and advances in sequencing technologies have resulted in rapid expansion of genetic testing. While BRCA1/2 are the most recognized genes linked to breast cancer, several laboratories now offer multi-gene panels to detect many risk-related mutations. IMPLICATIONS FOR NURSING PRACTICE: Genetic testing will be increasingly important in the prevention, diagnosis, and treatment of breast cancer. Oncology and advanced practice nurses must understand risk factors, significance of various genetic tests, and patient counseling.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.