Evidence map›Paper›PMID 25951227›Full record

Trial reportPloS one2015

Transcranial Electrical Stimulation over Dorsolateral Prefrontal Cortex Modulates Processing of Social Cognitive and Affective Information.

Massimiliano Conson, Domenico Errico, Elisabetta Mazzarella, Marianna Giordano, Dario Grossi, Luigi Trojano

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  11. The timing of confidence computations in human prefrontal cortex.Cortex; a journal devoted to the study of the nervous system and behavior · 2023
    Article
  12. Neuromodulatory effects of transcranial electrical stimulation on emotion regulation in internalizing psychopathologies.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Massimiliano ConsonNeuropsychology Laboratory, Department of Psychology, Second University of Naples, Caserta, Italy.
Domenico ErricoNeuropsychology Laboratory, Department of Psychology, Second University of Naples, Caserta, Italy.
Elisabetta MazzarellaDepartment of Neuromotor Physiology, Scientific Institute Foundation Santa Lucia, Rome, Italy.
Marianna GiordanoNeuropsychology Laboratory, Department of Psychology, Second University of Naples, Caserta, Italy.
Dario GrossiNeuropsychology Laboratory, Department of Psychology, Second University of Naples, Caserta, Italy.
Luigi TrojanoNeuropsychology Laboratory, Department of Psychology, Second University of Naples, Caserta, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent neurofunctional studies suggested that lateral prefrontal cortex is a domain-general cognitive control area modulating computation of social information. Neuropsychological evidence reported dissociations between cognitive and affective components of social cognition. Here, we tested whether performance on social cognitive and affective tasks can be modulated by transcranial direct current stimulation (tDCS) over dorsolateral prefrontal cortex (DLPFC). To this aim, we compared the effects of tDCS on explicit recognition of emotional facial expressions (affective task), and on one cognitive task assessing the ability to adopt another person's visual perspective. In a randomized, cross-over design, male and female healthy participants performed the two experimental tasks after bi-hemispheric tDCS (sham, left anodal/right cathodal, and right anodal/left cathodal) applied over DLPFC. Results showed that only in male participants explicit recognition of fearful facial expressions was significantly faster after anodal right/cathodal left stimulation with respect to anodal left/cathodal right and sham stimulations. In the visual perspective taking task, instead, anodal right/cathodal left stimulation negatively affected both male and female participants' tendency to adopt another's point of view. These findings demonstrated that concurrent facilitation of right and inhibition of left lateral prefrontal cortex can speed-up males' responses to threatening faces whereas it interferes with the ability to adopt another's viewpoint independently from gender. Thus, stimulation of cognitive control areas can lead to different effects on social cognitive skills depending on the affective vs. cognitive nature of the task, and on the gender-related differences in neural organization of emotion processing.

Indexed as

CognitionEmotionsTranscranial Direct Current StimulationAdultCross-Over StudiesDecision MakingFemaleHumansInhibition, PsychologicalInterpersonal RelationsMalePrefrontal CortexReaction TimeVisual PerceptionYoung Adult

Identifiers

PMID25951227
PMCPMC4423854

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.