ArticleJournal of aquatic animal health2015
Activity of Antibiotics against Mycobacterium Species Commonly Found in Laboratory Zebrafish.
Article in Journal of aquatic animal health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 23 citations in OpenAlex.
- Review of methods for detection and characterization of non-tuberculous mycobacteria in aquatic organisms.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024Review
- Treatment of non-tuberculosis mycobacteria skin infections.Frontiers in pharmacology · 2023Review
- Antibiotic Susceptibility of Mycobacteria Isolated from Ornamental Fish.Journal of veterinary research · 2022Article
- Mycobacteriosis and Infections with Non-tuberculous Mycobacteria in Aquatic Organisms: A Review.Microorganisms · 2020Review
- Extended insight into the Mycobacterium chelonae-abscessus complex through whole genome sequencing of Mycobacterium salmoniphilum outbreak and Mycobacterium salmoniphilum-like strains.Scientific reports · 2019Article
- Mycobacterium marinum infection in fish and man: epidemiology, pathophysiology and management; a review.The veterinary quarterly · 2018Review
- Environmental Screening of Aeromonas hydrophila, Mycobacterium spp., and Pseudocapillaria tomentosa in Zebrafish Systems.Journal of visualized experiments : JoVE · 2017Article
- Antibiotic treatment of zebrafish mycobacteriosis: tolerance and efficacy of treatments with tigecycline and clarithromycin.Journal of fish diseases · 2017Article
- Mycobacterium saopaulense sp. nov., a rapidly growing mycobacterium closely related to members of the Mycobacterium chelonae--Mycobacterium abscessus group.International journal of systematic and evolutionary microbiology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
The Zebrafish Danio rerio is a popular vertebrate model organism used in a wide range of research fields. Importance is placed on Zebrafish health and the maintenance of disease-free laboratory fish so that experimental studies are not inadvertently affected. Mycobacteriosis, a common infection of laboratory Zebrafish, is caused by several Mycobacterium species. Little is known regarding the potential of antibiotic treatment for Zebrafish mycobacteriosis; however, treatment of infected Zebrafish may be appropriate to maintain valuable strains. Here, we investigated, in vitro, the antibiotic susceptibility of both rapid- and slow-growing isolates of Mycobacterium species from laboratory Zebrafish. Antibiotic testing was carried out using a commercially available 96-well microtiter plate format. Results indicated that some but not all antibiotics tested were effective at inhibiting mycobacterial growth and that susceptibility varied among species and strains. Tigecycline, tobramycin, clarithromycin, and amikacin were most effective at broad inhibition of rapid-growing mycobacteria; whereas, amikacin, clarithromycin, and rifampin were effective at inhibiting all slow-growing M. marinum strains tested. Results support the potential for targeted antibiotic treatment of Zebrafish infected with mycobacteria, but additional testing should be carried out in vivo.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.