Evidence map›Paper›PMID 25950992›Full record

ArticleJournal of clinical laboratory analysis2016

Evaluation of the Alere NT-proBNP Test for Point of Care Testing.

Banafsheh Seyyed Khezri, Lena Carlsson, Anders Larsson

Abstract readEvaluation Study
In one paragraph

Article in Journal of clinical laboratory analysis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. BNP/NT-proBNP in pulmonary arterial hypertension: time for point-of-care testing?European respiratory review : an official journal of the European Respiratory Society · 2020
    Pooled it
  2. Review
  3. Melatonin and Comorbidities in Children with Autism Spectrum Disorder.Current developmental disorders reports · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Banafsheh Seyyed KhezriDepartment of Medical Sciences, Section of Clinical Chemistry, Uppsala University, Uppsala, Sweden.
Lena CarlssonDepartment of Medical Sciences, Section of Clinical Chemistry, Uppsala University, Uppsala, Sweden.
Anders LarssonDepartment of Medical Sciences, Section of Clinical Chemistry, Uppsala University, Uppsala, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe object of the study was to evaluate the Alere point of care NT-proBNP assay as a suitable alternative to the central laboratory method to provide short test turnaround times in primary care.

methodBlood NT-proBNP results obtained with the Alere assay (n = 100) were compared with serum NT-proBNP results analyzed by a Cobas 8000 analyzer (Roche Diagnostics, Mannheim, Germany).

resultsThere was a good agreement between the two NT-proBNP methods when used as a rule-out test for heart failure (HF) and the cut-off value <300 ng/l. A total of 47 samples gave values <300 ng/L with both methods and 51 samples gave values >300 with both methods. Thus, there was an agreement for 98% of the samples.

conclusionsThe study shows that the Alere NT-proBNP assay could be used in primary care permitting rapid NT-proBNP testing to rule out HF.

Indexed as

Point-of-Care TestingReagent Kits, DiagnosticHeart FailureHumansNatriuretic Peptide, BrainPeptide FragmentsRegression AnalysisNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)Reagent Kits, Diagnosticmethod evaluationNT-proBNPpoint of care testprimary care

Identifiers

PMID25950992
PMCPMC6807137

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.