ReviewVirulence2015
Insights into virulence factors determining the pathogenicity of Cronobacter sakazakii.
Review in Virulence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 74 citations in OpenAlex.
- Enteric-colonizedGut microbes · 2026Article
- Insights into the genomic features of the emerging pathogens Cronobacter malonaticus and Cronobacter turicensis.Folia microbiologica · 2026Article
- Whole-Genome Sequencing-Based Monitoring ofFood science & nutrition · 2026Article
- Optimized Viability-ddPCR with Triton X-100 Enhancement for Selective Detection of LiveJournal of microbiology and biotechnology · 2026Article
- Probiotic Saccharomyces boulardii Against Cronobacter sakazakii Infection: In Vitro and In Vivo Studies.Probiotics and antimicrobial proteins · 2026Article
- From Powder to Pathogen: A Systematic Review of Detection, Pathogenicity, and Mitigation ofInternational journal of microbiology · 2026Review
- Metagenomic Investigation of Intestinal Microbiota of Insectivorous Synanthropic Bats: Densoviruses, Antibiotic Resistance Genes, and Functional Profiling of Gut Microbial Communities.International journal of molecular sciences · 2025Article
- Pathogenic characterization and mechanism of sequence type 4 Cronobacter sakazakii derived from milk-based infant and baby foods.BMC microbiology · 2025Article
- NlpD as a crucial factor in desiccation resistance and biofilm formation in Cronobacter sakazakii.Scientific reports · 2025Article
- Characterization ofFrontiers in microbiology · 2025Article
- 2'-Fucosyllactose as a prebiotic modulates the probiotic responses ofCurrent research in food science · 2025Article
- Genomic Analysis ofInternational journal of molecular sciences · 2024Article
- Persistent enrichment of multidrug-resistant Klebsiella in oral and nasal communities during long-term starvation.Microbiome · 2024Article
- Characterization ofMicroorganisms · 2023Article
- Comprehensive Genomic Characterization ofMicroorganisms · 2023Article
- Cronobacter sakazakii Pyridoxal Kinase PdxY Mediated by TreR and pESA3 Is Essential for Vitamin BApplied and environmental microbiology · 2023Article
- Effects ofFoods (Basel, Switzerland) · 2023Article
- Screening of Antibiotic and Virulence Genes from Whole Genome SequencedAntibiotics (Basel, Switzerland) · 2023Article
- Foodborne pathogens in Africa: UnderstandingPublic health challenges · 2023Review
- Emerging of Multidrug-Resistant Cronobacter sakazakii Isolated from Infant Supplementary Food in China.Microbiology spectrum · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cronobacter sakazakii is an opportunistic pathogen associated with outbreaks of life-threatening necrotizing enterocolitis, meningitis and sepsis in neonates and infants. The pathogen possesses an array of virulence factors which aid in tissue adhesion, invasion and host cell injury. Although the identification and validation of C. sakazakii virulence factors has been hindered by availability of suitable neonatal animal model, various studies has reported outer membrane protein A (ompA) as a potential virulence marker. Various other plasmid associated genes such as filamentous hemagglutinin (fhaBC), Cronobacter plasminogen activator (cpa) and genes responsible for iron acquisition (eitCBAD and iucABD/iutA) have been reported in different strains of C. sakazakii. Besides these proposed virulence factors, several biophysical growth factors such as formation of biofilms and resistance to various environmental stresses also contributes to the pathogenic potential of this pathogen. This review provides an update on virulence determinants associated with the pathogenesis of C. sakazakii. The potential reservoirs of the pathogen, mode of transmission and epidemiology are also discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.