ReviewCurrent opinion in cell biology2015
Midbody: from cellular junk to regulator of cell polarity and cell fate.
Review in Current opinion in cell biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 76 citations in OpenAlex.
- Somatic cells non-autonomously control germline incomplete cytokinesis through FGF signaling.bioRxiv : the preprint server for biology · 2026Article
- Regulation of Citron kinase by CDK1 and Aurora B regulates midbody formation and stability.Journal of cell science · 2026Article
- CHI3L1 promotes cell division through activation of RhoA in lung cancer cells.Cell communication and signaling : CCS · 2025Article
- The midbody and midbody remnant: from cellular debris to signaling organelle with diagnostic and therapeutic potential.Molecular biology of the cell · 2025Review
- Prominosomes - a particular class of extracellular vesicles containing prominin-1/CD133?Journal of nanobiotechnology · 2025Review
- Extracellular vesicles, including large translating vesicles called midbody remnants, are released during the cell cycle.Molecular biology of the cell · 2024Article
- Satellite cell dynamics during skeletal muscle hypertrophy.Biochemical Society transactions · 2024Review
- Asymmetric division of stem cells and its cancer relevance.Cell regeneration (London, England) · 2024Review
- The role of midbody-associated mRNAs in regulating abscission.The Journal of cell biology · 2023Article
- Functional midbody assembly in the absence of a central spindle.The Journal of cell biology · 2022Article
- Midbody-Localized Aquaporin Mediates Intercellular Lumen Expansion During Early Cleavage of an Invasive Freshwater Bivalve.Frontiers in cell and developmental biology · 2022Article
- The Symmetry of Neural Stem Cell and Progenitor Divisions in the Vertebrate Brain.Frontiers in cell and developmental biology · 2022Review
- Rab14/MACF2 complex regulates endosomal targeting during cytokinesis.Molecular biology of the cell · 2021Article
- Secreted midbody remnants are a class of extracellular vesicles molecularly distinct from exosomes and microparticles.Communications biology · 2021Article
- Centrosome-centric view of asymmetric stem cell division.Open biology · 2021Review
- Asymmetric inheritance of epigenetic states in asymmetrically dividing stem cells.Current opinion in cell biology · 2020Review
- Article
- Cytokinesis and postabscission midbody remnants are regulated during mammalian brain development.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- The Flemmingsome reveals an ESCRT-to-membrane coupling via ALIX/syntenin/syndecan-4 required for completion of cytokinesis.Nature communications · 2020Article
- Actin reduction by MsrB2 is a key component of the cytokinetic abscission checkpoint and prevents tetraploidy.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
At late mitosis, the mother cell divides by the formation of a cleavage furrow, leaving two daughter cells connected by a thin intercellular bridge. During ingression of the cleavage furrow, the central spindle microtubules are compacted to form the structure known as the midbody (MB). The MB is situated within the intercellular bridge, with the abscission site sometimes occurring on one side of the MB. As a result of this one-sided (asymmetric) abscission, only one daughter cell can inherit the post-mitotic MB. Interestingly, recent studies have identified post-mitotic MBs as novel signaling platforms regulating stem cell fate and proliferation. Additionally, MBs were proposed to serve a role of polarity cues during the neurite outgrowth and apical lumen formation. Thus, abscission and MB inheritance is clearly a highly regulated cellular event that can affect development and various other cellular functions. In this review we discuss the latest findings regarding post-mitotic MB functions, as well as the machinery regulating MB inheritance and accumulation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.