Evidence map›Paper›PMID 25950455›Full record

ArticlePediatric research2015

Neonatal jaundice and risks of childhood allergic diseases: a population-based cohort study.

Chang-Ching Wei, Cheng-Li Lin, Te-Chun Shen, Chia-Hung Kao

Open access · bronzeAbstract read
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In one paragraph

Article in Pediatric research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
10.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Chang-Ching Wei1] Children's Hospital, China Medical University Hospital, Taichung, Taiwan [2] College of Medicine, China Medical University, Taichung, Taiwan.
Cheng-Li Lin1] College of Medicine, China Medical University, Taichung, Taiwan [2] Management Office for Health Data, China Medical University Hospital, Taichung, Taiwan.
Te-Chun Shen1] College of Medicine, China Medical University, Taichung, Taiwan [2] Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Taichung, Taiwan.
Chia-Hung Kao1] Graduate Institute of Clinical Medicine Science and School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan [2] Department of Nuclear Medicine and PET Center, China Medical University Hospital, Taichung, Taiwan.
China Medical University · TWChina Medical University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOnly a few studies have systemically analyzed the association between neonatal jaundice and childhood-onset allergic diseases.

methodsFrom 2000 to 2007, 27,693 neonates with newly diagnosed neonatal jaundice and 55,367 matched nonneonatal jaundice cohorts were identified. The incidences and hazard ratios (HRs) of five allergic diseases, namely allergic conjunctivitis (AC), allergic rhinitis (AR), atopic dermatitis (AD), asthma, and urticaria, by the end of 2008 were calculated.

resultsThe incidence density and HRs of the five allergic diseases were greater in the neonatal jaundice cohort than in the nonneonatal jaundice cohort, and the HRs declined modestly with age. The HRs for AR (HR = 2.51, 95% confidence interval (CI) = 2.43-2.59) and AD (HR = 2.51, 95% CI = 2.40-2.62) were the highest, and that for urticaria was the lowest (HR = 2.06, 95% CI = 1.94-2.19). The HRs of allergic diseases were substantially greater for boys and those requiring phototherapy. The HRs of the allergic diseases, except urticaria (HR = 2.49, 95% CI = 1.57-3.97), were not significantly different between the neonatal jaundice regardless of whether the patients received exchange transfusion.

conclusionNeonatal jaundice is associated with the development of allergic diseases in early childhood.

Indexed as

Cohort StudiesFemaleHumansHypersensitivityIncidenceInfant, NewbornJaundice, NeonatalMale

Identifiers

PMID25950455
OpenAlexW602748300

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.