ReviewPediatric research2015
Efficacy and safety of acupuncture in children: an overview of systematic reviews.
Review in Pediatric research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05025384 (Auricular Acupressure as an Adjunct Treatment for Opioid Tapering in a Pediatric Cardiac Intensive Care Unit), which is not on this map. Cited by 57 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Auricular Acupressure as an Adjunct Treatment for Opioid Tapering in a Pediatric Cardiac Intensive Care Unit: A Pilot Feasibility Study
Who cites it
57 citing papers in PubMed, 5 syntheses or guidelines pooled it, 126 citations in OpenAlex.
- Meta-analysis of acupuncture combined therapies for amblyopia: efficacy and safety insights.Frontiers in medicine · 2025Pooled it
- Acupuncture for Treating Attention Deficit Hyperactivity Disorder in Children: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2023Pooled it
- Effect of Acupuncture on the p38 Signaling Pathway in Several Nervous System Diseases: A Systematic Review.International journal of molecular sciences · 2020Pooled it
- Pooled it
- Acupuncture for pediatric chronic pain: a systematic review.Jornal de pediatriaPooled it
- Electroacupuncture for juvenile idiopathic arthritis: clinical efficacy and its role in modulating pyroptosis and autophagy pathways.Clinical rheumatology · 2025Trial
- Laser acupuncture improving functional chronic constipation in children: a randomized controlled trial.Lasers in medical science · 2023Trial
- Comparison of Electroacupuncture and Body Acupuncture on Gastrocnemius Muscle Tone in Children with Spastic Cerebral Palsy: A Single Blinded, Randomized Controlled Pilot Trial.Chinese journal of integrative medicine · 2020Trial
- Effect of minimal acupuncture for infantile colic: a multicentre, three-armed, single-blind, randomised controlled trial (ACU-COL).Acupuncture in medicine : journal of the British Medical Acupuncture Society · 2017Trial
- Nocturnal enuresis in children between laser acupuncture and medical treatment: a comparative study.Lasers in medical science · 2017Trial
- Does noninvasive electrical stimulation of acupuncture points reduce heelstick pain in neonates?Acta paediatrica (Oslo, Norway : 1992) · 2016Trial
- The role of acupuncture as a complementary therapy for sepsis: a narrative review of the evidence and future trial directions.Frontiers in medicine · 2026Review
- Article
- Electroacupuncture ameliorates Autism Spectrum Disorder via modulating the gut-brain axis depending on the integrity of vagus nerve.Translational psychiatry · 2025Article
- East Asian traditional medicine for attention-deficit hyperactivity disorder in children and adolescents: a scoping review.BMC complementary medicine and therapies · 2025Article
- International Consensus Guidelines on the Safe and Evidence-Based Practice of Mesotherapy: A Multidisciplinary Statement.Journal of clinical medicine · 2025Article
- Complementary medicine for post-tonsillectomy pain management in children: a network meta-analysis.Annals of medicine and surgery (2012) · 2025Review
- Tiny needles, major benefits: acupuncture in child health.BMC pediatrics · 2025Article
- Effects of Electroacupuncture on Syt3 and GluA2 in Rats With Limb Spasms After Intracerebral Hemorrhage.Brain and behavior · 2025Article
- Research Trends and Hotspots of Acupuncture Therapy on Allergic Diseases From 2004 to 2024: A Bibliometric Analysis.Journal of multidisciplinary healthcare · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, acupuncture has increasingly being integrated into pediatric health care. It was used on ~150,000 children (0.2%). We aim to update the evidence for the efficacy and safety of acupuncture for children and evaluate the methodological qualities of these studies to improve future research in this area. We included 24 systematic reviews, comprising 142 randomized controlled trials (RCTs) with 12,787 participants. Only 25% (6/24) reviews were considered to be high quality (10.00 ± 0.63). High-quality systematic reviews and Cochrane systematic reviews tend to yield neutral or negative results (P = 0.052, 0.009 respectively). The efficacy of acupuncture for five diseases (Cerebral Palsy (CP), nocturnal enuresis, tic disorders, amblyopia, and pain reduction) is promising. It was unclear for hypoxic ischemic encephalopathy, attention deficit hyperactivity disorder, mumps, autism spectrum disorder (ASD), asthma, nausea/vomiting, and myopia. Acupuncture is not effective for epilepsy. Only six reviews reported adverse events (AEs) and no fatal side effects were reported. The efficacy of acupuncture for some diseases is promising and there have been no fatal side effects reported. Further high-quality studies are justified, with five diseases in particular as research priorities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.