ArticleBioMed research international2015
Prehospital volume therapy as an independent risk factor after trauma.
Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prehospital coagulation management and fluid replacement therapy in patients with multiple and/or severe injuries - A systematic review and clinical practice guideline update.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Pooled it
- Prehospital Blood Product Resuscitation for Trauma: A Systematic Review.Shock (Augusta, Ga.) · 2016Pooled it
- Reality of treatment for severely injured patients: are there age-specific differences?BMC emergency medicine · 2024Article
- Liberal intraoperative fluid management leads to increased complication rates in geriatric patients with hip fracture.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023Article
- Is prehospital intubation of severely injured children in accordance with guidelines?BMC emergency medicine · 2022Article
- Changes in transfusion and fluid therapy practices in severely injured children: an analysis of 5118 children from the TraumaRegister DGU®.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
- The volume of infusion fluids correlates with treatment outcomes in critically ill trauma patients.Frontiers in medicine · 2022Article
- Article
- Natural language processing of prehospital emergency medical services trauma records allows for automated characterization of treatment appropriateness.The journal of trauma and acute care surgery · 2020Article
- Enhanced prehospital volume therapy does not lead to improved outcomes in severely injured patients with severe traumatic brain injury.BMC emergency medicine · 2019Article
- Is Prehospital Time Important for the Treatment of Severely Injured Patients? A Matched-Triplet Analysis of 13,851 Patients from the TraumaRegister DGU®.BioMed research international · 2019Article
- Volume replacement during trauma resuscitation: a brief synopsis of current guidelines and recommendations.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2017Review
- [Volume therapy in the severely injured patient : Recommendations and current guidelines].Der Unfallchirurg · 2017Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrehospital volume therapy remains widely used after trauma, while evidence regarding its disadvantages is growing. The primary objective of this study was to investigate the volume administered in a prehospital setting as an independent risk factor for mortality. MATERIAL AND
methodsPatients who met the following criteria were analyzed retrospectively: Injury Severity Score=16, primary admission (between 2002 and 2010), and age=16 years. The following data had to be available: volume administered (including packed red cells), blood pressure, Glasgow Coma Scale, therapeutic measures, and laboratory results. Following a univariate analysis, independent risk factors for mortality after trauma were investigated using a multivariate regression analysis.
resultsA collective of 7,641 patients met the inclusion criteria, showing that increasing volumes administered in a prehospital setting were an independent risk factor for mortality (odds ratio: 1.34). This tendency was even more pronounced in patients without severe traumatic brain injury (TBI) (odds ratio: 2.71), while the opposite tendency was observed in patients with TBI.
conclusionsPrehospital volume therapy in patients without severe TBI represents an independent risk factor for mortality. In such cases, respiratory and circulatory conditions should be stabilized during permissive hypotension, and patient transfer should not be delayed.
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