Evidence map›Paper›PMID 25949935›Full record

ReviewWorld journal of nephrology2015

Impact of obesity on kidney function and blood pressure in children.

Wei Ding, Wai W Cheung, Robert H Mak

Abstract readReview
In one paragraph

Review in World journal of nephrology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. A prospective analysis to assess the multifactorial risk of childhood-onset hypertension: the ExAMIN Youth SA study.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Observational
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Seasonal variation of blood pressure in children.Pediatric nephrology (Berlin, Germany) · 2021
    Review
  12. Article
  13. Review
  14. Article
  15. Chronic kidney disease in children.Clinical kidney journal · 2016
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wei DingWei Ding, Wai W Cheung, Robert H Mak, Department of Pediatrics, Rady Children's Hospital, University of California, San Diego, CA 92093-0634, United States.
Wai W CheungWei Ding, Wai W Cheung, Robert H Mak, Department of Pediatrics, Rady Children's Hospital, University of California, San Diego, CA 92093-0634, United States.
Robert H MakWei Ding, Wai W Cheung, Robert H Mak, Department of Pediatrics, Rady Children's Hospital, University of California, San Diego, CA 92093-0634, United States.

Funding

National Center for Muscle Rehabilitation ResearchR24HD050837 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LIEBER, RICHARD L., WARD, SAMUEL RICHARD · 2005 to 2014
$7.2M
NICHD NIH HHS R24 HD050837
6 · The paper itself

Abstract

In recent years, obesity has become an increasingly important epidemic health problem in children and adolescents. The prevalence of the overweight status in children grew from 5% to 11% from 1960s to 1990s. The epidemic of obesity has been paralleled by an increase in the incidence of chronic kidney disease (CKD) and hypertension. Results of several studies have demonstrated that obesity and metabolic syndrome were independent predictors of renal injury. The pathophysiology of obesity related hypertension is complex, including activation of sympathetic nervous system, renin angiotensin aldosterone system, hyperinsulinemia and inflammation. These same mechanisms likely contribute to the development of increased blood pressure in children. This review summarizes the recent epidemiologic data linking obesity with CKD and hypertension in children, as well as the potential mechanisms.

Indexed as

Blood pressureChronic kidney diseaseEnd-stage renal failureHypertensionObesity

Identifiers

PMID25949935
PMCPMC4419131

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.