Evidence map›Paper›PMID 25949932›Full record

ReviewWorld journal of nephrology2015

Pathogenesis of glomerular haematuria.

Claudia Yuste, Eduardo Gutierrez, Angel Manuel Sevillano, Alfonso Rubio-Navarro, Juan Manuel Amaro-Villalobos, Alberto Ortiz, Jesus Egido, Manuel Praga, Juan Antonio Moreno

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of nephrology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

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  12. The mucosal immune system and IgA nephropathy.Seminars in immunopathology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Claudia YusteClaudia Yuste, Department of Nephrology, Gregorio Marañon Hospital, 28007 Madrid, Spain.
Eduardo GutierrezClaudia Yuste, Department of Nephrology, Gregorio Marañon Hospital, 28007 Madrid, Spain.
Angel Manuel SevillanoClaudia Yuste, Department of Nephrology, Gregorio Marañon Hospital, 28007 Madrid, Spain.
Alfonso Rubio-NavarroClaudia Yuste, Department of Nephrology, Gregorio Marañon Hospital, 28007 Madrid, Spain.
Juan Manuel Amaro-VillalobosClaudia Yuste, Department of Nephrology, Gregorio Marañon Hospital, 28007 Madrid, Spain.
Alberto OrtizClaudia Yuste, Department of Nephrology, Gregorio Marañon Hospital, 28007 Madrid, Spain.
Jesus EgidoClaudia Yuste, Department of Nephrology, Gregorio Marañon Hospital, 28007 Madrid, Spain.
Manuel PragaClaudia Yuste, Department of Nephrology, Gregorio Marañon Hospital, 28007 Madrid, Spain.
Juan Antonio MorenoClaudia Yuste, Department of Nephrology, Gregorio Marañon Hospital, 28007 Madrid, Spain.
Hospital General Universitario Gregorio Marañón · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Haematuria was known as a benign hallmark of some glomerular diseases, but over the last decade, new evidences pointed its negative implications on kidney disease progression. Cytotoxic effects of oxidative stress induced by hemoglobin, heme, or iron released from red blood cells may account for the tubular injury observed in human biopsy specimens. However, the precise mechanisms responsible for haematuria remain unclear. The presence of red blood cells (RBCs) with irregular contours and shape in the urine indicates RBCs egression from the glomerular capillary into the urinary space. Therefore glomerular haematuria may be a marker of glomerular filtration barrier dysfunction or damage. In this review we describe some key issues regarding epidemiology and pathogenesis of haematuric diseases as well as their renal morphological findings.

Indexed as

Chronic kidney diseaseDysmorphic red blood cellsGlomerular filtration barrierHaematuriaMicroscopic haematuriaPathogenesis

Identifiers

PMID25949932
PMCPMC4419128
OpenAlexW2321762643

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.