Evidence map›Paper›PMID 25949469›Full record

ArticleNDT plus2010

Fulminant primary manifestations of Wegener's granulomatosis might not be pauci-immune.

Ulf Schönermarck, Maja Grahovac, Miklós Sárdy, Michael Dolch, Andreas Wollenberg

Abstract readCase Reports
In one paragraph

Article in NDT plus, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ulf SchönermarckNephrology Division, Department I of Internal Medicine.
Maja GrahovacDepartment of Dermatology and Allergy.
Miklós SárdyDepartment of Dermatology and Allergy.
Michael DolchDepartment of Anaesthesiology , University Hospital Munich-Grosshadern, Ludwig-Maximilians-University, Munich , Germany.
Andreas WollenbergDepartment of Dermatology and Allergy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wegener's granulomatosis is an ANCA-associated small vessel vasculitis. Because histologically immune complex deposits are frequently lacking, the term pauci-immune has been introduced for this subgroup. We report a patient with fulminant, severe PR3-ANCA-positive Wegener's granulomatosis and multi-organ involvement (upper respiratory tract, lung, kidneys, skin and general symptoms), who showed pronounced immunoglobulin and complement deposits within the skin biopsy. Our observation supports the hypothesis that immune complex deposits may be under-recognized in early lesions of ANCA-associated Wegener's granulomatosis.

Indexed as

ANCApauci-immunevasculitisWegener’s granulomatosis

Identifiers

PMID25949469
PMCPMC4421412

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.