ArticleJournal of laboratory physicians
Comparison of Bone Mineral Density, T-Scores and Serum Zinc between Diabetic and Non Diabetic Postmenopausal Women with Osteoporosis.
Article in Journal of laboratory physicians. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 21 citations in OpenAlex.
- Association between Pro-oxidant-Antioxidant balance and high-sensitivity C-reactive protein in type 2 diabetes mellitus: A Study on Postmenopausal Women.Endocrinology, diabetes & metabolism · 2023Article
- Bone Health in Aging Men: Does Zinc and Cuprum Level Matter?Biomolecules · 2021Article
- Inhibition of tanshinone IIA on renin activity protected against osteoporosis in diabetic mice.Pharmaceutical biology · 2020Article
- Forearm bone density is not elevated in Inuit women with impaired fasting glucose or type 2 diabetes mellitus.International journal of circumpolar health · 2019Article
- Variables to Be Monitored via Biomedical Sensors for Complete Type 1 Diabetes Mellitus Management: An Extension of the "On-Board" Concept.Journal of diabetes research · 2018Review
- Effects of vitamin D combined with pioglitazone hydrochloride on bone mineral density and bone metabolism in Type 2 diabetic nephropathy.Bioscience reports · 2017Article
- Effects of a7nAChR agonist on the tissue estrogen receptor expression of castrated rats.International journal of clinical and experimental pathology · 2015Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextPostmenopausal osteoporosis is a public health problem. Diabetics are at increased risk of osteoporosis-related fractures. Zinc (Zn) has a role in collagen metabolism, and its levels are altered in diabetes.
aimsThe aim was to compare bone mineral density (BMD), T-score and serum Zn between diabetic and nondiabetic postmenopausal women with osteoporosis to see if they influence increased fracture risk in diabetes. SETTINGS AND
designIt is a cross.sectional study conducted at Department of Biochemistry, Jawaharlal Nehru Medical College, Belgaum. MATERIALS AND
methodsThirty type 2 diabetic and 30 age-matched (aged 45-75 years) nondiabetic Dual energy X-ray absorptiometry (DEXA) confirmed postmenopausal osteoporotics were included from January 2011 to March 2012. Serum Zn was analyzed by atomic absorption spectrophotometry. STATISTICAL ANALYSIS USED: Mean and standard deviation of the parameters of the two groups were computed and compared by unpaired Student's t-test. Relationship between variables was measured by Karl Pearson's correlation co-efficient. A statistical significance is set at 5% level of significance (P < 0.05).
resultsT-score was significantly higher in diabetics compared with nondiabetics (-2.84 ± 0.42 vs. -3.22 ± 0.74) P < 0.05. BMD and serum Zn of diabetics showed a significant positive correlation with body mass index (BMI).
conclusionsType 2 diabetic postmenopausal osteoporotics have a higher T-score than the nondiabetics. High BMI in type-2 diabetes mellitus (T2DM) may contribute to high BMD and may be a protective factor against zincuria. Increased fracture risk in T2DM could be due to other factors like poor bone quality due to hyperglycemia rather than BMD. Strict glycemic control is of paramount importance.
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