ArticleJournal of laboratory physicians
A Leap above Friedewald Formula for Calculation of Low-Density Lipoprotein-Cholesterol.
Article in Journal of laboratory physicians. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Article
- Choosing the right equation for calculating indirect LDL-Cholesterol (LDL-C) in adult Pakistani population: Evaluation of seven equations using big data analytics.Practical laboratory medicine · 2024Article
- Comparison between the Friedewald, Martin and Sampson Equations and LDL-C Quantification by Ultracentrifugation in a Mexican Population.Diagnostics (Basel, Switzerland) · 2024Article
- Martin's Formula As the Most Suitable Method for Estimation of Low-Density Lipoprotein Cholesterol in Indian Population.Journal of laboratory physicians · 2023Article
- Simultaneous Electrochemical Detection of LDL and MDA-LDL Using Antibody-Ferrocene or Anthraquinone Conjugates Coated Magnetic Beads.International journal of molecular sciences · 2023Article
- Antibody-Ferrocene Conjugates as a Platform for Electro-Chemical Detection of Low-Density Lipoprotein.Molecules (Basel, Switzerland) · 2022Article
- Comparison of Formula-Based Methods with Diverse TGL: VLDL-C Ratio for Calculating LDL-C in a Tertiary Care Hospital.Journal of laboratory physicians · 2022Article
- Article
- Detection of Low Density Lipoprotein-Comparison of Electrochemical Immuno- and Aptasensor.Sensors (Basel, Switzerland) · 2021Article
- Is data mining approach a best fit formula for estimation of low-density lipoprotein cholesterol?Journal of family medicine and primary care · 2021Article
- Evaluation of eight formulas for LDL-C estimation in Iranian subjects with different metabolic health statuses.Lipids in health and disease · 2019Article
- New modified Friedewald formulae for estimating low-density lipoprotein cholesterol according to triglyceride levels: extraction and validation.Endocrine · 2018Article
- Developing a Modified Low-Density Lipoprotein (M-LDL-C) Friedewald's Equation as a Substitute for Direct LDL-C Measure in a Ghanaian Population: A Comparative Study.Journal of lipids · 2018Article
- Attenuating the rate of total body fat accumulation and alleviating liver damage by oral administration of vitamin D-enriched edible mushrooms in a diet-induced obesity murine model is mediated by an anti-inflammatory paradigm shift.BMC gastroenterology · 2017Article
- Calculation of LDL-Cholesterol vs. Direct Homogenous Assay.Journal of clinical laboratory analysis · 2017Article
- Comparison of Formulas for Calculating Low-density Lipoprotein Cholesterol in General Population and High-risk Patients with Cardiovascular Disease.Korean circulation journal · 2016Article
- Assessing the Validity of Friedewald's Formula and Anandraja's Formula For Serum LDL-Cholesterol Calculation.Journal of clinical and diagnostic research : JCDR · 2015Article
- Friedewald's equation for calculating LDL-cholesterol: Is it the time to say "Goodbye" and adopt direct LDL cholesterol methods?Pakistan journal of medical sciencesArticle
- Calculated low density lipoprotein cholesterol: Its relevance in Indian perspective.Indian heart journalArticle
- Correlation of Friedewald's calculated low-density lipoprotein cholesterol levels with direct low-density lipoprotein cholesterol levels in a tertiary care hospital.International journal of applied & basic medical researchArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose was to compare the different calculated methods of low-density lipoprotein cholesterol (LDL-C) estimation and to determine which of them correlate best with the direct method. MATERIALS AND
methodsThe records of 480 samples for lipid profile were analyzed. Apart from the direct method, LDL-C was calculated by Friedewald low-density lipoprotein cholesterol method (F-LDL-C), modified Friedewald low-density lipoprotein cholesterol method (MF-LDL-C), and Anandaraja low-density lipoprotein cholesterol method (A-LDL-C). Paired t-test and Pearson correlation were evaluated between the different methods. Degree of agreement between the calculated methods and direct method was detected by Bland-Altman graphical plots.
resultsA strong correlation was found between all calculated LDL-C methods and direct low-density lipoprotein cholesterol method (D-LDL-C) assay, that is, F-LDL-C versus D-LDL-C = 0.94; A-LDL-C versus D-LDL-C = 0.93 and MF-LDL-C versus D-LDL-C = 0.95. No statistically significant difference was found between D-LDL-C and MF-LDL-C. Bland-Altman plot for MF-LDL-C showed minimal negative bias.
conclusionsThe study pointed out that MF-LDL-C correlated maximally with D-LDL-C estimation at all levels of triglycerides and MF-LDL-C can be used in place of D-LDL-C when the direct method cannot be afforded.
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