ArticleJournal of anaesthesiology, clinical pharmacology
Comparison of dexmedetomidine-propofol versus fentanyl-propofol for insertion of laryngeal mask airway.
Article in Journal of anaesthesiology, clinical pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The trial behind it
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Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Effects of Remifentanil and Dexmedetomidine with Propofol on Laryngeal Mask Airway Insertion, Hemodynamic Stability, and Pharyngolaryngeal Morbidity: A Prospective Study of 80 Patients.Medical science monitor : international medical journal of experimental and clinical research · 2025Trial
- Comparison of the Effects of Propofol-Dexmedetomidine and Thiopental-Dexmedetomidine Combinations on the Success of Classical Laryngeal Mask Airway Insertions, Hemodynamic Responses, and Pharyngolaryngeal Morbidity.Medicina (Kaunas, Lithuania) · 2025Trial
- Remimazolam dose for successful insertion of a supraglottic airway device with opioids: a dose-determination study using Dixon's up-and-down method.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023Trial
- The effect of dexmedetomidine pretreatment on the median effective bolus dose of propofol for facilitating laryngeal mask airway insertion.Journal of anesthesia · 2017Trial
- Propofol-fentanyl versus propofol-dexmedetomidine: Hemodynamics and recovery during supraumbilical surgery.Bioinformation · 2026Article
- The different doses of sufentanil combined with nalmefene in bronchoscopy: a systematic review and meta-analysis.Journal of thoracic disease · 2024Article
- Comparative evaluation of i-gelIndian journal of anaesthesia · 2019Article
- Analgesic Effect and Hemodynamic Changes Due to Dexmedetomidine Versus Fentanyl During Elective Colonoscopy: A Double-Blind Randomized Clinical Trial.Anesthesiology and pain medicine · 2018Article
- Dexmedetomidine with propofol versus fentanyl with propofol for insertion of Proseal laryngeal mask airway: A randomized, double-blinded clinical trial.Journal of anaesthesiology, clinical pharmacologyArticle
- Role of opioids as coinduction agent with propofol and their effect on apnea time, recovery time, and sedation score.International journal of critical illness and injury scienceArticle
- I-Gel versus laryngeal mask airway (LMA) classic as a conduit for tracheal intubation using ventilating bougie.Journal of anaesthesiology, clinical pharmacologyArticle
- Low-dose Succinylcholine to Facilitate Laryngeal Mask Airway Insertion: A Comparison of Two Doses.Anesthesia, essays and researchesArticle
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsLaryngeal mask airway (LMA) insertion requires anesthesia and suppression of airway reflexes. In search of an optimal drug, we compared dexmedetomidine and fentanyl, in combination with propofol for insertion of LMA. MATERIAL AND
methodsThis study was a prospective double blind randomized study. Eighty patients of ASA class 1&2 were randomly divided into two groups of 40 each. Group D received dexmedetomidine 1 mcg/kg and group F received fentanyl 1 mcg/kg intravenously (IV) over 2 minutes. For induction, propofol 2mg/kg was given IV and 90 seconds later LMA was inserted. We observed apnea time, heart rate, respiratory rate, non invasive blood pressure and oxygen saturation before induction, 30 seconds after induction, 1, 3, 5, 10 and 15 minutes after insertion of LMA. Patient's response to LMA insertion like coughing, gagging or any movement were noted and scored. Statistical analysis of data was done using student t test for parametric data, Chi-square test for non parametric data and SPSS 15.0 for windows software.
results37 (92.5%) patients of group D and 35 (87.5%) patients of group F had LMA insertion score of <2 and 5 (12.5%) patients of group F had score >2. Adverse events to insertion of LMA and hemodynamic variables were comparable in both the groups. Number of patients developing apnoea was larger and apnoea times were longer in group F compared to group D. When compared to group F, group D showed an increased respiratory rate.
conclusionDexmedetomidine can be a comparable alternative to fentanyl as an adjuvant to propofol for providing optimum insertion conditions for LMA and preservation of respiration.
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