ArticleBMJ case reports2015
Acute liver injury associated with a newer formulation of the herbal weight loss supplement Hydroxycut.
Article in BMJ case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 23 citations in OpenAlex.
- Hepatotoxicity of dietary supplements containingPharmaceutical biology · 2025Review
- Hepatotoxicity due to herbal dietary supplements: Past, present and the future.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2022Review
- Risks Associated with the Use of Garcinia as a Nutritional Complement to Lose Weight.Nutrients · 2021Review
- Article
- United States Pharmacopeia (USP) comprehensive review of the hepatotoxicity of green tea extracts.Toxicology reports · 2020Review
- Finding the bad actor: Challenges in identifying toxic constituents in botanical dietary supplements.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2019Review
- Is obesity rather than the dietary supplement used for weight reduction the cause of liver injury?JGH open : an open access journal of gastroenterology and hepatology · 2018Review
- Hepatotoxicity by Dietary Supplements: A Tabular Listing and Clinical Characteristics.International journal of molecular sciences · 2016Review
- Scientific and Regulatory Perspectives in Herbal and Dietary Supplement Associated Hepatotoxicity in the United States.International journal of molecular sciences · 2016Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite the widespread use of herbal and dietary supplements (HDS), serious cases of hepatotoxicity have been reported. The popular herbal weight loss supplement, Hydroxycut, has previously been implicated in acute liver injury. Since its introduction, Hydroxycut has undergone successive transformations in its formulation; yet, cases of liver injury have remained an ongoing problem. We report a case of a 41-year-old Hispanic man who developed acute hepatocellular liver injury with associated nausea, vomiting, jaundice, fatigue and asterixis attributed to the use of a newer formulation of Hydroxycut, SX-7 Clean Sensory. The patient required hospitalisation and improved with supportive therapy. Despite successive transformations in its formulation, potential liver injury appears to remain an ongoing problem with Hydroxycut. Our case illustrates the importance of obtaining a thorough medication history, including HDS, regardless of new or reformulated product marketing efforts.
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Registered trials
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