ArticleAmerican journal of epidemiology2015
Cardiometabolic risk factors in young adults who were born preterm.
Article in American journal of epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers, 7 of them syntheses that pooled it.
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Who cites it
127 citing papers in PubMed, 7 syntheses or guidelines pooled it, 227 citations in OpenAlex.
- Socioeconomic outcomes in very preterm/very low birth weight adults: individual participant data meta-analysis.Pediatric research · 2025Pooled it
- Body composition in preterm infants: a systematic review on measurement methods.Pediatric research · 2023Pooled it
- Gestational age at birth and body size from infancy through adolescence: An individual participant data meta-analysis on 253,810 singletons in 16 birth cohort studies.PLoS medicine · 2023Pooled it
- The association between late preterm birth and cardiometabolic conditions across the life course: A systematic review and meta-analysis.Paediatric and perinatal epidemiology · 2022Pooled it
- Association of maternal prenatal selenium concentration and preterm birth: a multicountry meta-analysis.BMJ global health · 2021Pooled it
- Completeness of Retention Data and Determinants of Attrition in Birth Cohorts of Very Preterm Infants: A Systematic Review.Frontiers in pediatrics · 2021Pooled it
- Association of Low Birth Weight and Premature Birth With the Risk of Metabolic Syndrome: A Meta-Analysis.Frontiers in pediatrics · 2020Pooled it
- Formula with large, milk phospholipid-coated lipid droplets in late-moderate preterm infants: a double-blind RCT.Pediatric research · 2025Trial
- PREPARE: A Stepped-Wedge Cluster-Randomized Trial to Evaluate Whether Risk Stratification Can Reduce Preterm Deliveries Among Patients With Suspected or Confirmed Preterm Preeclampsia.Hypertension (Dallas, Tex. : 1979) · 2023Trial
- Late preterm birth has direct and indirect effects on infant gut microbiota development during the first six months of life.Acta paediatrica (Oslo, Norway : 1992) · 2017Trial
- Growth, metabolic markers, and cognition in 8-year old children born prematurely, follow-up of a randomized controlled trial with essential fatty acids.European journal of pediatrics · 2016Trial
- Gestational age at birth and the risk of disability pension in early adulthood: a whole-population register study of people born in Finland in 1987-90.International journal of epidemiology · 2026Article
- Article
- Postnatal conditional growth and size and body composition at 24 months in moderate-and-late preterm children.Pediatric research · 2026Article
- Structural and Functional Abnormalities in the Preterm Heart: From Development to Adulthood.Journal of the American Heart Association · 2026Review
- Bronchopulmonary dysplasia and extremely preterm birth: time for a broader perspective on long-term outcomes.European respiratory review : an official journal of the European Respiratory Society · 2026Review
- Associations of glyphosate and aminomethylphosphonic acid (AMPA) concentrations with birth outcomes in pregnant women from the Midwestern U.S.International journal of hygiene and environmental health · 2026Article
- Blood and adipose tissue DNA methylation in adults born preterm with a very low birth weight - a sibling comparison study.Epigenomics · 2026Article
- Integrated bioinformatics and machine learning to explore the common mechanisms and potential biomarkers between periodontitis and preterm birth.Frontiers in cell and developmental biology · 2026Article
- Combined Burden of Preterm and Low Birthweight Births in Greece: A Nationwide Time-Trend Analysis.Cureus · 2025Article
67 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
Abstract
Adults who were born preterm with a very low birth weight have higher blood pressure and impaired glucose regulation later in life compared with those born at term. We investigated cardiometabolic risk factors in young adults who were born at any degree of prematurity in the Preterm Birth and Early Life Programming of Adult Health and Disease (ESTER) Study, a population-based cohort study of individuals born in 1985-1989 in Northern Finland. In 2009-2011, 3 groups underwent clinical examination: 134 participants born at less than 34 gestational weeks (early preterm), 242 born at 34-36 weeks (late preterm), and 344 born at 37 weeks or later (controls). Compared with controls, adults who were born preterm had higher body fat percentages (after adjustment for sex, age, and cohort (1985-1986 or 1987-1989), for those born early preterm, difference = 6.2%, 95% confidence interval (CI): 0.4, 13.2; for those born late preterm, difference = 8.0%, 95% CI: 2.4, 13.8), waist circumferences, blood pressure (for those born early preterm, difference = 3.0 mm Hg, 95% CI: 0.9, 5.1; for those born late preterm, difference = 1.7, 95% CI: -0.1, 3.4), plasma uric acid levels (for those born early preterm, difference = 20.1%, 95% CI: 7.9, 32.3; for those born late preterm, difference = 20.2%, 95% CI: 10.7, 30.5), alanine aminotransferase levels, and aspartate transaminase levels. They were also more likely to have metabolic syndrome (for those born early preterm, odds ratio = 3.7, 95% CI: 1.6, 8.2; for those born late preterm, odds ratio = 2.5, 95% CI: 1.2, 5.3). Elevated levels of conventional and emerging risk factors suggest a higher risk of cardiometabolic disease later in life. These risk factors are also present in the large group of adults born late preterm.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.