Evidence map›Paper›PMID 25947417›Full record

ArticleInfection2016

Rapid regression of Kaposi's sarcoma of the hard palate under therapy with boosted elvitegravir-containing fixdose antiretroviral combination therapy.

Gundolf Schüttfort, Timo Wolf, Phillip de Leuw, Gerrit Kann, Maximilian Blume, Hans-Reinhard Brodt, Christoph Stephan

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Involvement of Sex Hormones and Their Receptors in the Pathogenesis of Classic Kaposi's Sarcoma in Xinjiang.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Gundolf SchüttfortDepartment for Internal Medicine II/Infectious Diseases, Goethe-University Hospital, Frankfurt am Main, Germany. dcgundolf@yahoo.de.
Timo WolfDepartment for Internal Medicine II/Infectious Diseases, Goethe-University Hospital, Frankfurt am Main, Germany.
Phillip de LeuwDepartment for Internal Medicine II/Infectious Diseases, Goethe-University Hospital, Frankfurt am Main, Germany.
Gerrit KannDepartment for Internal Medicine II/Infectious Diseases, Goethe-University Hospital, Frankfurt am Main, Germany.
Maximilian BlumeDepartment for Orofacial Surgery, Goethe-University Hospital, Frankfurt am Main, Germany.
Hans-Reinhard BrodtDepartment for Internal Medicine II/Infectious Diseases, Goethe-University Hospital, Frankfurt am Main, Germany.
Christoph StephanDepartment for Internal Medicine II/Infectious Diseases, Goethe-University Hospital, Frankfurt am Main, Germany.
University Hospital Frankfurt · DEGoethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionKaposi's sarcoma (KS) is a rare vascular tumor that may occur in a severe, rapidly progressive form, namely in HIV/AIDS patients. HIV-associated KS mainly affects the skin and mucous membranes. CASE PRESENTATION: We report about an HIV-positive patient who presented with an exophytic growing tumor in the region of the hard palate and severe problems regarding his dental status. Histological examination revealed evidence of AIDS-related KS. Antiretroviral therapy initiation with elvitegravir/cobicistat/emtricitabine(FTC)/tenofovirdisoproxilfumarat (E/c/F/T-fix dose combination) resulted in rapid complete remission of the KS within 2 months.

conclusionIn this case of a treatment-naive HIV-infected patient with coexisting KS, antiretroviral therapy with E/c/FTC/TDF was very well suited to achieve rapid complete remission of KS.

Indexed as

AdultAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveHIV InfectionsHumansMalePalatal NeoplasmsPalate, HardQuinolonesSarcoma, KaposiTreatment OutcomeAnti-HIV AgentselvitegravirQuinolonesElvitegravirHIVKaposi

Identifiers

PMID25947417
OpenAlexW210997052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.