ArticleCardiovascular diabetology2015
Association of peripheral nerve conduction in diabetic neuropathy with subclinical left ventricular systolic dysfunction.
Article in Cardiovascular diabetology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 36 citations in OpenAlex.
- Association of muscle performance and heart rate variability in middle-aged type 2 diabetes mellitus.Journal of family medicine and primary care · 2025Article
- Development and validation of a prediction model of left ventricular systolic dysfunction in type 2 diabetes mellitus.Quantitative imaging in medicine and surgery · 2025Article
- Left ventricular systolic dyssynchrony: a novel imaging marker for early assessment of myocardial damage in Chinese type 2 diabetes mellitus patients with normal left ventricular ejection fraction and normal myocardial perfusion.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Association of left ventricular longitudinal myocardial function with subclinical right ventricular dysfunction in type 2 diabetes mellitus.Cardiovascular diabetology · 2021Article
- Diabetic microvascular complications are associated with reduced global longitudinal strain independent of atherosclerotic coronary artery disease in asymptomatic patients with diabetes mellitus: a cross-sectional study.BMC cardiovascular disorders · 2021Article
- Effect of heart rate on left ventricular longitudinal myocardial function in type 2 diabetes mellitus.Cardiovascular diabetology · 2021Article
- Impact of diabetes mellitus on left ventricular longitudinal function of patients with non-ischemic dilated cardiomyopathy.Cardiovascular diabetology · 2020Article
- Positive effect of dapagliflozin on left ventricular longitudinal function for type 2 diabetic mellitus patients with chronic heart failure.Cardiovascular diabetology · 2020Article
- Association between Circulating B-Type Natriuretic Peptide and Diabetic Peripheral Neuropathy: A Cross-Sectional Study of a Chinese Type 2 Diabetic Population.Journal of diabetes research · 2020Article
- Utility of strain imaging in conjunction with heart failure stage classification for heart failure patient management.Journal of echocardiography · 2019Review
- Sensory Neuropathy Affects Cardiac miRNA Expression Network TargetingInternational journal of molecular sciences · 2019Article
- Left atrial, ventricular and atrio-ventricular strain in patients with subclinical heart dysfunction.The international journal of cardiovascular imaging · 2019Article
- Association of left ventricular myocardial dysfunction with diabetic polyneuropathy.Journal of medical ultrasonics (2001) · 2019Article
- Future Perspectives for Management of Stage A Heart Failure.Journal of atherosclerosis and thrombosis · 2018Article
- Potential impact of SGLT2 inhibitors on left ventricular diastolic function in patients with diabetes mellitus.Heart failure reviews · 2018Review
- Impact of left ventricular longitudinal functional mechanics on the progression of diastolic function in diabetes mellitus.The international journal of cardiovascular imaging · 2017Article
- Impact of overweight on left ventricular function in type 2 diabetes mellitus.Cardiovascular diabetology · 2017Article
- Diagnostic approaches for diabetic cardiomyopathy.Cardiovascular diabetology · 2017Review
- Xanthine Oxidase Activity in Type 2 Diabetes Mellitus Patients with and without Diabetic Peripheral Neuropathy.Journal of diabetes research · 2016Article
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13 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundSubclinical left ventricular (LV) longitudinal myocardial systolic dysfunction occurs in patients with diabetes mellitus (DM) and preserved LV ejection fraction (LVEF), and is closely related to DM-related complications. However, the association of diabetic neuropathy (DN) with subclinical LV systolic longitudinal dysfunction in such patients has not been fully clarified.
methodsThe subjects of this study were 112 consecutive DM patients with preserved LVEF (all ≥50%) without coronary artery disease and overt heart failure (aged 59 ± 14 years; 60 women, 52 men). Global longitudinal strain (GLS) was determined as the average peak strain of 18 segments from the three standard apical views, and was expressed as an absolute value. DN was diagnosed by experienced diabetologists. Median, ulnar, and sural nerves were subjected to motor and sensory nerve conduction studies. F-wave latency was defined as the minimum F-wave latency after a total of 16 stimulations of the tibial nerve.
resultsForty-one (37%) patients were clinically diagnosed with DN. LV functions of DM patients with and without DN were similar except for GLS being significantly smaller in patients with than in patients without DN (18 ± 2% vs. 20 ± 2%, p < 0.001). It was noteworthy that, of the parameters for the nerve conduction study, only F-wave latency correlated with GLS (r = -0.34, p < 0.001), and also was identified as an independent determinative value of GLS in a multivariate linear regression model (β = -0.25, p = 0.001) even after adjustment for other closely related GLS factors.
conclusionsMonitoring of F-wave latency may aid early detection of not only DN but also subclinical LV dysfunction. Joint planning of assessment by diabetologists and cardiologists is therefore advisable for better management of DM patients.
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