ArticleInvestigative radiology2015
Free-breathing liver perfusion imaging using 3-dimensional through-time spiral generalized autocalibrating partially parallel acquisition acceleration.
Article in Investigative radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Accelerated Abdominal MRI: A Review of Current Methods and Applications.Journal of magnetic resonance imaging : JMRI · 2025Review
- Improving motion robustness of 3D MR fingerprinting with a fat navigator.Magnetic resonance in medicine · 2023Article
- 4D Golden-Angle Radial MRI at Subsecond Temporal Resolution.NMR in biomedicine · 2023Article
- Portable Perfusion Phantom Offers Quantitative Dynamic Contrast-Enhanced Magnetic Resonance Imaging for Accurate Prostate Cancer Grade Stratification: A Pilot Study.Academic radiology · 2021Article
- Diffusion-Weighted and Dynamic Contrast-Enhanced MRI Derived Imaging Metrics for Stereotactic Body Radiotherapy of Pancreatic Ductal Adenocarcinoma: Preliminary Findings.Tomography (Ann Arbor, Mich.) · 2020Article
- Article
- Realistic 4D MRI abdominal phantom for the evaluation and comparison of acquisition and reconstruction techniques.Magnetic resonance in medicine · 2019Article
- Abdominal DCE-MRI reconstruction with deformable motion correction for liver perfusion quantification.Medical physics · 2018Article
- Single breath-hold 3D cardiac TNMR in biomedicine · 2018Article
- Quantitative perfusion imaging of neoplastic liver lesions: A multi-institution study.Scientific reports · 2018Article
- Rigid-body motion correction of the liver in image reconstruction for golden-angle stack-of-stars DCE MRI.Magnetic resonance in medicine · 2018Article
- Modification of population based arterial input function to incorporate individual variation.Magnetic resonance imaging · 2018Article
- Free-Breathing 3D Liver Perfusion Quantification Using a Dual-Input Two-Compartment Model.Scientific reports · 2017Article
- Feasibility of through-time spiral generalized autocalibrating partial parallel acquisition for low latency accelerated real-time MRI of speech.Magnetic resonance in medicine · 2017Article
- Quantitative Methods in Abdominal MRI: Perfusion Imaging.Topics in magnetic resonance imaging : TMRI · 2017Review
- Compressed sensing for body MRI.Journal of magnetic resonance imaging : JMRI · 2017Review
- Multiparametric MR Imaging in Abdominal Malignancies.Magnetic resonance imaging clinics of North America · 2016Review
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Authors and funding
10 authors.
Funding
Abstract
objectivesThe goal of this study was to develop free-breathing high-spatiotemporal resolution dynamic contrast-enhanced liver magnetic resonance imaging using non-Cartesian parallel imaging acceleration, and quantitative liver perfusion mapping. MATERIALS AND
methodsThis study was approved by the local institutional review board and written informed consent was obtained from all participants. Ten healthy subjects and 5 patients were scanned on a Siemens 3-T Skyra scanner. A stack-of-spirals trajectory was undersampled in-plane with a reduction factor of 6 and reconstructed using 3-dimensional (3D) through-time non-Cartesian generalized autocalibrating partially parallel acquisition. High-resolution 3D images were acquired with a true temporal resolution of 1.6 to 1.9 seconds while the subjects were breathing freely. A dual-input single-compartment model was used to retrieve liver perfusion parameters from dynamic contrast-enhanced magnetic resonance imaging data, which were coregistered using an algorithm designed to reduce the effects of dynamic contrast changes on registration. Image quality evaluation was performed on spiral images and conventional images from 5 healthy subjects.
resultsImages with a spatial resolution of 1.9 × 1.9 × 3 mm3 were obtained with whole-liver coverage. With an imaging speed of better than 2 s/vol, free-breathing scans were achieved and dynamic changes in enhancement were captured. The overall image quality of free-breathing spiral images was slightly lower than that of conventional long breath-hold Cartesian images, but it provided clinically acceptable or better image quality. The free-breathing 3D images were registered with almost no residual motion in liver tissue. After the registration, quantitative whole-liver 3D perfusion maps were obtained and the perfusion parameters are all in good agreement with the literature.
conclusionsThis high-spatiotemporal resolution free-breathing 3D liver imaging technique allows voxelwise quantification of liver perfusion.
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