Evidence map›Paper›PMID 25946563›Full record

ArticleOrganic letters2015

Synthesis of Polycyclic Nitrogen Heterocycles via Cascade Pd-Catalyzed Alkene Carboamination/Diels-Alder Reactions.

Derick R White, John P Wolfe

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Organic letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Derick R WhiteDepartment of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, Michigan 48109-1055, United States.
John P WolfeDepartment of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, Michigan 48109-1055, United States.

Funding

New Reactions for Heterocycle SynthesisR01GM071650 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WOLFE, JOHN P · 2005 to 2010
$1.2M
New Alkene Difunctionalization Reactions for Organic SynthesisR01GM098314 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WOLFE, JOHN P · 2011 to 2014
$1.1M
NIGMS NIH HHS GM 071650NIGMS NIH HHS R01 GM071650NIGMS NIH HHS R01 GM098314
6 · The paper itself

Abstract

Cascade Pd-catalyzed alkene carboamination/Diels-Alder reactions between bromodienes and amines bearing two pendant alkenes are described. These transformations generate 4 bonds, 3 rings, and 3-5 stereocenters to afford polycyclic nitrogen heterocycles with high diastereoselectivity.

Indexed as

AlkenesAminationCatalysisHeterocyclic CompoundsMolecular StructureNitrogenPalladiumPolycyclic CompoundsAlkenesHeterocyclic CompoundsNitrogenPalladiumPolycyclic Compounds

Identifiers

PMID25946563
PMCPMC4480637

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.