Evidence map›Paper›PMID 25946253›Full record

ArticleMemorias do Instituto Oswaldo Cruz2015

T-helper 17-related cytokines and IgE antibodies during hepatitis A virus infection in children.

Jorge L Trujillo-Ochoa, Karla F Corral-Jara, Griselda Escobedo-Meléndez, Mauricio Realpe, Arturo Panduro, Sonia Roman, Nora A Fierro

Open access · diamondAbstract read
In one paragraph

Article in Memorias do Instituto Oswaldo Cruz, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Jorge L Trujillo-Ochoaaff1.
Karla F Corral-Jaraaff1.
Griselda Escobedo-Meléndezaff4.
Mauricio RealpeDepartamento de Medicina Veterinaria, Centro Universitario de Ciencias Biológicas y Agropecuarias, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico.
Arturo Panduroaff1.
Sonia Romanaff4.
Nora A Fierroaff1.
Arab Foundations Forum · JOUniversidad de Guadalajara · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We determined the serum IgE levels and T-helper (Th)17-related cytokines during distinct hepatitis A virus (HAV)-induced clinical courses in children. A significantly higher concentration of macrophage inflammatory protein 3α, interleukin (IL)-17E and IL-17F in HAV-infected children with intermediate liver injury compared with those with minor liver damage was found. A reduction in the IgE levels in those patients who showed the highest levels of IL-17F in the group of intermediate liver injury was found. The data suggested that the Th17-related profile is associated with the severity of HAV infection and might play a role on the modulation achieved by HAV during allergies.

Indexed as

AdolescentAlanine TransaminaseAspartate AminotransferasesChildChild, PreschoolFemaleHepatitis AHepatitis A Virus, HumanHumansImmunoglobulin EInfantInfant, NewbornInterleukin-17LiverMaleRetrospective StudiesAlanine TransaminaseAspartate AminotransferasesImmunoglobulin EInterleukin-17

Identifiers

PMID25946253
PMCPMC4489460
OpenAlexW2047957264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.