Evidence map›Paper›PMID 25945150›Full record

ArticleOxidative medicine and cellular longevity2015

Age-related responses in circulating markers of redox status in healthy adolescents and adults during the course of a training macrocycle.

Athanasios Zalavras, Ioannis G Fatouros, Chariklia K Deli, Dimitris Draganidis, Anastasios A Theodorou, Dimitrios Soulas, Yiannis Koutsioras, Yiannis Koutedakis, Athanasios Z Jamurtas

Abstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
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  8. Article
  9. Oxidative Stress in Children and Adolescents: Insights Into Human Biology.American journal of human biology : the official journal of the Human Biology Council · 2025
    Review
  10. The MuCAYACJC open · 2024
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Cutting edge concepts: Does bilirubin enhance exercise performance?Frontiers in sports and active living · 2022
    Review
  16. Article
  17. Review
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  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Athanasios ZalavrasDepartment of Physical Education & Sport Science, University of Thessaly, Karies, 42100 Trikala, Greece.
Ioannis G FatourosDepartment of Physical Education & Sport Science, University of Thrace, 69100 Komotini, Greece ; Department of Kinesiology, Institute for Research & Technology, Thessaly, 42100 Trikala, Greece.
Chariklia K DeliDepartment of Physical Education & Sport Science, University of Thessaly, Karies, 42100 Trikala, Greece ; Department of Kinesiology, Institute for Research & Technology, Thessaly, 42100 Trikala, Greece.
Dimitris DraganidisDepartment of Physical Education & Sport Science, University of Thrace, 69100 Komotini, Greece.
Anastasios A TheodorouDepartment of Physical Education & Sport Science, University of Thessaly, Karies, 42100 Trikala, Greece.
Dimitrios SoulasDepartment of Physical Education & Sport Science, University of Thessaly, Karies, 42100 Trikala, Greece.
Yiannis KoutsiorasDepartment of Physical Education & Sport Science, University of Thessaly, Karies, 42100 Trikala, Greece.
Yiannis KoutedakisDepartment of Physical Education & Sport Science, University of Thessaly, Karies, 42100 Trikala, Greece ; Department of Physical Education & Sport Science, University of Thrace, 69100 Komotini, Greece ; School of Sport, Performing Arts & Leisure, Wolverhampton University, Gorway Road, Walsall, West Midlands WS1 3BD, UK.
Athanasios Z JamurtasDepartment of Physical Education & Sport Science, University of Thessaly, Karies, 42100 Trikala, Greece ; Department of Kinesiology, Institute for Research & Technology, Thessaly, 42100 Trikala, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Redox status changes during an annual training cycle in young and adult track and field athletes and possible differences between the two age groups were assessed. Forty-six individuals (24 children and 22 adults) were assigned to four groups: trained adolescents, (TAD, N = 13), untrained adolescents (UAD, N = 11), trained adults (TA, N = 12), and untrained adults (UA, N = 10). Aerobic capacity and redox status related variables [total antioxidant capacity (TAC), glutathione (GSH), catalase activity, TBARS, protein carbonyls (PC), uric acid, and bilirubin] were assessed at rest and in response to a time-trial bout before training, at mid- and posttraining. TAC, catalase activity, TBARS, PC, uric acid, and bilirubin increased and GSH declined in all groups in response to acute exercise independent of training status and age. Training improved aerobic capacity, TAC, and GSH at rest and in response to exercise. Age affected basal and exercise-induced responses since adults demonstrated a greater TAC and GSH levels at rest and a greater rise of TBARS, protein carbonyls, and TAC and decline of GSH in response to exercise. Catalase activity, uric acid, and bilirubin responses were comparable among groups. These results suggest that acute exercise, age, and training modulate the antioxidant reserves of the body.

Indexed as

ExerciseOxidative StressAdolescentAdultAge FactorsAntioxidantsBilirubinBiomarkersCatalaseFemaleGlutathioneHumansMaleOxygen ConsumptionProtein CarbonylationUric AcidAntioxidantsBilirubinBiomarkersCatalaseGlutathioneUric Acid

Identifiers

PMID25945150
PMCPMC4402481

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.