Evidence map›Paper›PMID 25945068›Full record

ArticleInternational medical case reports journal2015

Acute orbital apex syndrome and rhino-orbito-cerebral mucormycosis.

Ursula M Anders, Elise J Taylor, Joseph R Martel, James B Martel

Open access · goldAbstract readCase Reports
In one paragraph

Article in International medical case reports journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Title of the Article: Paranasal Mucormycosis in COVID-19 Patient.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Neuroimaging in the Diagnostic Evaluation of Eye Pain.Current pain and headache reports · 2016
    Review
  17. Fungal infections of the orbit.Indian journal of ophthalmology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ursula M AndersResearch Center, Martel Eye Medical Group, Rancho Cordova, CA, USA.
Elise J TaylorResearch Center, Martel Eye Medical Group, Rancho Cordova, CA, USA.
Joseph R MartelResearch Center, Martel Eye Medical Group, Rancho Cordova, CA, USA ; Graduate Medical Education, California Northstate University College of Medicine, Elk Grove, CA, USA ; Department of Ophthalmology, Dignity Health, Carmichael, CA, USA.
James B MartelResearch Center, Martel Eye Medical Group, Rancho Cordova, CA, USA ; Graduate Medical Education, California Northstate University College of Medicine, Elk Grove, CA, USA ; Department of Ophthalmology, Dignity Health, Carmichael, CA, USA.
California Northstate University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo demonstrate the successful clinical identification and management of rhino-orbital mucormycosis, a fungal infection with a high mortality rate. PATIENTS AND

methodsA diabetic male patient with a headache and orbital apex syndrome in the right eye was examined using computed tomography (CT) and magnetic resonance imaging (MRI) for a possible fungal infection. Endoscopic surgical resection was performed and a pathology sample was taken. Specimens were prepared with Gömöri methenamine silver and hematoxylin and eosin staining. The patient was treated with liposomal amphotericin B 400 mg daily, followed by posaconazole 400 mg twice daily.

resultsCT and MRI revealed a mass of the right sphenoid spreading into the orbit, indicative of a fungal infection. The biopsy confirmed the diagnosis of mucormycosis. Complete recovery of eyelid and oculomotor function was achieved after 10 months of treatment, although the patient continues to suffer from irreversible blindness in the right eye due to optic nerve atrophy. He has been without signs or symptoms of recurrence.

conclusionPatients with rhino-orbito-cerebral mucormycosis need extensive surgical and medical treatment to maximize outcomes. Success requires multidisciplinary management.

Indexed as

amphotericin Bdiabetes mellitusnephrotoxicityophthalmoplegiaposaconazolesixth nerve palsy

Identifiers

PMID25945068
PMCPMC4407820
OpenAlexW2045651385

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.