Evidence map›Paper›PMID 25944828›Full record

ReviewPlant physiology2015

Group VII Ethylene Response Factors Coordinate Oxygen and Nitric Oxide Signal Transduction and Stress Responses in Plants.

Daniel J Gibbs, Jorge Vicente Conde, Sophie Berckhan, Geeta Prasad, Guillermina M Mendiondo, Michael J Holdsworth

Open access · greenAbstract readReview
In one paragraph

Review in Plant physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
24.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 198 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Integration of NO and HPlant communications · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. CaBMC plant biology · 2025
    Article
  10. Review
  11. Review
  12. Review
  13. Article
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  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
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27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Daniel J GibbsSchool of Biosciences, University of Birmingham, Edgbaston B15 2TT, United Kingdom (D.J.G.); andDepartment of Plant and Crop Sciences, University of Nottingham, Sutton Bonington Campus, Leicestershire LE12 5RD, United Kingdom (J.V.C., S.B., G.P., G.M.M., M.J.H.) d.gibbs@bham.ac.uk michael.holdsworth@nottingham.ac.uk.
Jorge Vicente CondeSchool of Biosciences, University of Birmingham, Edgbaston B15 2TT, United Kingdom (D.J.G.); andDepartment of Plant and Crop Sciences, University of Nottingham, Sutton Bonington Campus, Leicestershire LE12 5RD, United Kingdom (J.V.C., S.B., G.P., G.M.M., M.J.H.).
Sophie BerckhanSchool of Biosciences, University of Birmingham, Edgbaston B15 2TT, United Kingdom (D.J.G.); andDepartment of Plant and Crop Sciences, University of Nottingham, Sutton Bonington Campus, Leicestershire LE12 5RD, United Kingdom (J.V.C., S.B., G.P., G.M.M., M.J.H.).
Geeta PrasadSchool of Biosciences, University of Birmingham, Edgbaston B15 2TT, United Kingdom (D.J.G.); andDepartment of Plant and Crop Sciences, University of Nottingham, Sutton Bonington Campus, Leicestershire LE12 5RD, United Kingdom (J.V.C., S.B., G.P., G.M.M., M.J.H.).
Guillermina M MendiondoSchool of Biosciences, University of Birmingham, Edgbaston B15 2TT, United Kingdom (D.J.G.); andDepartment of Plant and Crop Sciences, University of Nottingham, Sutton Bonington Campus, Leicestershire LE12 5RD, United Kingdom (J.V.C., S.B., G.P., G.M.M., M.J.H.).ORCID http://orcid.org/0000-0001-7716-4255
Michael J HoldsworthSchool of Biosciences, University of Birmingham, Edgbaston B15 2TT, United Kingdom (D.J.G.); andDepartment of Plant and Crop Sciences, University of Nottingham, Sutton Bonington Campus, Leicestershire LE12 5RD, United Kingdom (J.V.C., S.B., G.P., G.M.M., M.J.H.) d.gibbs@bham.ac.uk michael.holdsworth@nottingham.ac.uk.
University of Birmingham · GBUniversity of Nottingham · GB

Funding

Biotechnology and Biological Sciences Research Council BB/K000144/1Biotechnology and Biological Sciences Research Council BB/M002268/1Biotechnology and Biological Sciences Research Council BB/M007820/1
6 · The paper itself

Abstract

The group VII ethylene response factors (ERFVIIs) are plant-specific transcription factors that have emerged as important regulators of abiotic and biotic stress responses, in particular, low-oxygen stress. A defining feature of ERFVIIs is their conserved N-terminal domain, which renders them oxygen- and nitric oxide (NO)-dependent substrates of the N-end rule pathway of targeted proteolysis. In the presence of these gases, ERFVIIs are destabilized, whereas an absence of either permits their accumulation; ERFVIIs therefore coordinate plant homeostatic responses to oxygen availability and control a wide range of NO-mediated processes. ERFVIIs have a variety of context-specific protein and gene interaction partners, and also modulate gibberellin and abscisic acid signaling to regulate diverse developmental processes and stress responses. This update discusses recent advances in our understanding of ERFVII regulation and function, highlighting their role as central regulators of gaseous signal transduction at the interface of ethylene, oxygen, and NO signaling.

Indexed as

Signal TransductionAmino Acid MotifsEthylenesGene Expression Regulation, PlantHomeostasisNitric OxideOxygenPhylogenyPlant Growth RegulatorsPlant ProteinsPlantsProteolysisStress, PhysiologicalTranscription FactorsethyleneEthylenesNitric OxideOxygenPlant Growth RegulatorsPlant ProteinsTranscription Factors

Identifiers

PMID25944828
PMCPMC4577381
OpenAlexW2110043425

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.