Evidence map›Paper›PMID 25944711›Full record

ArticleInternational journal of cancer2015

Comparing sensitivity and specificity of screening mammography in the United States and Denmark.

Katja Kemp Jacobsen, Ellen S O'Meara, Dustin Key, Diana S M Buist, Karla Kerlikowske, Ilse Vejborg, Brian L Sprague, Elsebeth Lynge, My von Euler-Chelpin

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in International journal of cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  4. Observational
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  12. Malmö Breast ImaginG database: objectives and development.Journal of medical imaging (Bellingham, Wash.) · 2023
    Article
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  19. Function-related Indicators and Outcomes of Screening Mammography in Older Women: Evidence from the Breast Cancer Surveillance Consortium Cohort.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Katja Kemp JacobsenDepartment of Public Health, University of Copenhagen, Copenhagen K, Denmark.
Ellen S O'MearaGroup Health Research Institute, Seattle, WA, USA.
Dustin KeyGroup Health Research Institute, Seattle, WA, USA.
Diana S M BuistGroup Health Research Institute, Seattle, WA, USA.
Karla KerlikowskeDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
Ilse VejborgCenter of Diagnostic Imaging, Copenhagen University Hospital, Rigshospitalet, Denmark.
Brian L SpragueDepartment of Surgery, University of Vermont, Burlington, VT, USA.
Elsebeth LyngeDepartment of Public Health, University of Copenhagen, Copenhagen K, Denmark.
My von Euler-ChelpinDepartment of Public Health, University of Copenhagen, Copenhagen K, Denmark.
Kaiser Permanente Washington Health Research Institute · USUniversity of Copenhagen · DKCopenhagen University Hospital · DKUniversity of California, San Francisco · USUniversity of Vermont · US

Funding

Risk-based Imaging Strategies to Improve Breast Cancer Surveillance OutcomesP01CA154292 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Diana L Miglioretti · 2011 to 2026
$52.9M
Vermont Screening Process Documentation UnitU54CA163303 · NCI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI SPRAGUE, BRIAN L · 2011 to 2017
$6.4M
Statistical Methods for Estimation of Benefits & Harms of Repeat Cancer ScreeningR03CA182986 · NCI · UNIVERSITY OF PENNSYLVANIA · PI HUBBARD, REBECCA · 2014 to 2015
$160k
NCI NIH HHS HHSN261201100031CNCI NIH HHS P01 CA154292NCI NIH HHS P01CA154292NCI NIH HHS R03 CA182986NCI NIH HHS R03CA182986NCI NIH HHS U54 CA163303NCI NIH HHS U54CA163303PHS HHS HHSN261201100031C
6 · The paper itself

Abstract

Delivery of screening mammography differs substantially between the United States (US) and Denmark. We evaluated whether there are differences in screening sensitivity and specificity. We included screens from women screened at age 50-69 years during 1996-2008/2009 in the US Breast Cancer Surveillance Consortium (BCSC) (n = 2,872,791), and from two population-based mammography screening programs in Denmark (Copenhagen, n = 148,156 and Funen, n = 275,553). Women were followed-up for 1 year. For initial screens, recall rate was significantly higher in BCSC (17.6%) than in Copenhagen (4.3%) and Funen (3.1%). Sensitivity was fairly similar in BCSC (91.8%) and Copenhagen (90.5%) and Funen (92.5%). At subsequent screens, recall rates were 8.8%, 1.8% and 1.4% in BCSC, Copenhagen and Funen, respectively. The BCSC sensitivity (82.3%) was lower compared with that in Copenhagen (88.9%) and Funen (86.9%), but when stratified by time since last screen, the sensitivity was similar. For both initial and subsequent screenings, the specificity of screening in BCSC (83.2% and 91.6%) was significantly lower than that in Copenhagen (96.6% and 98.8%) and Funen (97.9% and 99.2%). By taking time since last screen into account, it was found that American and Danish women had the same probability of having their asymptomatic cancers detected at screening. However, the majority of women free of asymptomatic cancers experienced more harms in terms of false-positive findings in the US than in Denmark.

Indexed as

AgedBreast NeoplasmsDenmarkEarly Detection of CancerFemaleHumansMammographyMass ScreeningMiddle AgedSensitivity and SpecificityUnited StatesBreast Cancer Surveillance Consortiummammographic performancemass screeningsensitivityspecificity

Identifiers

PMID25944711
PMCPMC4537675
OpenAlexW2116357175

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.