ReviewCurrent opinion in pediatrics2015
Recent advances in the pathogenesis and management of biliary atresia.
Review in Current opinion in pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Comparison of laparoscopic portoenterostomy and open portoenterostomy for the treatment of biliary atresia.Surgical endoscopy · 2019Pooled it
- Liver transplantation for biliary atresia: a systematic review.Pediatric surgery international · 2017Pooled it
- Long-term outcomes of liver transplantation in biliary atresia: a 20-year single-center study.Pediatric surgery international · 2026Article
- Biliary atresia-related liver fibrosis.Frontiers in cell and developmental biology · 2026Review
- Mesenchymal stem cells in intrahepatic and extrahepatic biliary diseases: mechanisms and therapeutic applications.Frontiers in cell and developmental biology · 2026Review
- A two-hit model in biliary atresia: cooperative viral-bacterial activation of MMP7 via TLR4/NF-κB signaling.Pediatric research · 2025Article
- Biliary atresia: the development, pathological features, and classification of the bile duct.Pediatric surgery international · 2024Review
- Development of liver inflammatory injury in biliary atresia: from basic to clinical research.Pediatric surgery international · 2023Review
- Association between mitochondrial and nuclear DNA damages and cellular senescence in the patients with biliary atresia undergoing Kasai portoenterostomy and liver transplantation.Medical molecular morphology · 2022Article
- The need for early Kasai portoenterostomy: a Western Pediatric Surgery Research Consortium study.Pediatric surgery international · 2022Article
- Detection of Cytomegalovirus Infection in Infants with Biliary Atresia: A Meta-analysis.Avicenna journal of medicine · 2022Review
- Systemic cytokine profiles in biliary atresia.PloS one · 2022Article
- Chronic Drug-Induced Liver Injury: Updates and Future Challenges.Frontiers in pharmacology · 2021Review
- Article
- Gene Expression Signatures Associated With Survival Times of Pediatric Patients With Biliary Atresia Identify Potential Therapeutic Agents.Gastroenterology · 2019Article
- Prominin-1 Promotes Biliary Fibrosis Associated With Biliary Atresia.Hepatology (Baltimore, Md.) · 2019Article
- Development and Validation of Novel Diagnostic Models for Biliary Atresia in a Large Cohort of Chinese Patients.EBioMedicine · 2018Article
- Association of T-helper cell cytokine level with age in patients with biliary atresia: a preliminary study.World journal of pediatrics : WJP · 2018Article
- Newborn screening for biliary atresia in the United States.Pediatric surgery international · 2017Review
- Expression of programmed death-1 and its ligands in the liver of biliary atresia.World journal of pediatrics : WJP · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
purpose of reviewThe purpose of this study is to review advances in both the pathogenesis and clinical management of biliary atresia. RECENT
findingsImmunologic studies have further characterized roles of helper T-cells, B-cells, and natural killer cells in the immune dysregulation following viral replication within and damage of biliary epithelium. Prominin-1-expressing portal fibroblasts may play an integral role in the biliary fibrosis associated with biliary atresia. A number of genetic polymorphisms have been characterized as leading to susceptibility for biliary atresia. Postoperative corticosteroid therapy is not associated with greater transplant-free survival. Newborn screening may improve outcomes of infants with biliary atresia and may also provide a long-term cost benefit. SUMMARY: Although recent advances have enhanced our understanding of pathogenesis and clinical management, biliary atresia remains a significant challenge requiring further investigation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.