Evidence map›Paper›PMID 25943758›Full record

ArticleEnvironmental health : a global access science source2015

Effects of a fruit-vegetable dietary pattern on oxidative stress and genetic damage in coke oven workers: a cross-sectional study.

Zheng Xie, Haijiang Lin, Renfei Fang, Weiwei Shen, Shuguang Li, Bo Chen

Abstract read
In one paragraph

Article in Environmental health : a global access science source, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  10. Serum and Dietary Folate and Vitamin BOxidative medicine and cellular longevity · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zheng XieSchool of Public Health, Peking University Health Science Center, 38 Xueyuan Road, Beijing, 100191, P. R. China. xiezheng@bjmu.edu.cn.
Haijiang LinTaizhou City Center for Disease Control and Prevention, 608 The east China sea avenue, Taizhou city, Zhejiang Province, 318000, P. R. China. linhaijiang@hotmail.com.
Renfei FangSchool of Public Health, Peking University Health Science Center, 38 Xueyuan Road, Beijing, 100191, P. R. China. frfbjmu@126.com.
Weiwei ShenTaizhou City Center for Disease Control and Prevention, 608 The east China sea avenue, Taizhou city, Zhejiang Province, 318000, P. R. China. shengo8899@126.com.
Shuguang LiKey Laboratory of Public Health Safety of Ministry of Education, School of Public Health, Fudan University, 138 Yixueyuan Road, Shanghai, 20032, P. R. China. leeshuguang@fudan.edu.cn.
Bo ChenKey Laboratory of Public Health Safety of Ministry of Education, School of Public Health, Fudan University, 138 Yixueyuan Road, Shanghai, 20032, P. R. China. chenb@fudan.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoke oven workers (COWs) are exposed to high level of genotoxic chemicals that induce oxidative stress and genetic damage. The dietary intake of certain types of foods may reverse these effects.

methodsWe conducted a cross-sectional study with 51 topside COWs, 79 other COWs, and 67 controls, to assess the effects of dietary patterns on oxidative stress and genetic damage.

resultsCompared to the controls, both topside and other COWs had significantly higher urinary 1-hydroxypyrene levels, serum oxidant levels [malondialdehyde, (MDA)], and genetic damage [micronucleus (MN) frequency & 8-oxo-2'-deoxyguanosine (8-OH-dG)], but lower antioxidant levels [superoxide dismutase (SOD) and glutathione peroxidase, (GPx)]. The fruit-vegetable (FV) dietary pattern was positively correlated with serum SOD levels and negative correlated with serum MDA, MN frequency, and urinary 8-OH-dG. COWs with an FV patter in the highest quartile (Q4) had significantly increased antioxidant levels (SOD and GPx) and decreased oxidant levels (MDA) and genetic damage (MN frequency and 8-OH-dG) than those with an FV pattern in the lowest quartile (Q1).

conclusionCompared to control subjects, COWs had increased oxidative stress and genetic damage. A FV dietary pattern may reverse oxidative stress and genetic damage in COWs.

Indexed as

DietDNA DamageMetallurgyOccupational ExposureAdultChinaCross-Sectional StudiesFactor Analysis, StatisticalFruitHumansMaleMiddle AgedOxidative StressVegetables

Identifiers

PMID25943758
PMCPMC4428115

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.