Evidence map›Paper›PMID 25943629›Full record

ArticleBMC musculoskeletal disorders2015

Is the state of health of rheumatoid arthritis patients receiving adequate treatment, predictable? - Results of a survey.

Rudolf Puchner, Hans Peter Brezinschek, Josef Fritz, Manfred Herold, Monika Mustak, Thomas Nothnagl, Stephan E Puchner, Andrea Studnicka-Benke, Burkhard F Leeb

Abstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rudolf PuchnerRheumatologist and Qualified Health Care Manager, Wels, Austria. rudolf.puchner@cc-net.at.
Hans Peter BrezinschekRheumatology and Immunology Division, Department of Internal Medicine, Medical University of Graz, Graz, Austria. hans.peter.brezinsek@meduni-graz.at.
Josef FritzDepartment of Medical Statistics, Informatics and Health Economics, Medical University of Innsbruck, Innsbruck, Austria. josef.fritz@i-med.ac.at.
Manfred HeroldDepartment of Internal Medicine I, Medical University of Innsbruck, Innsbruck, Austria. manfred.herold@i-med.ac.at.
Monika MustakDepartment of Internal Medicine II, Kaiser Franz Josef Hospital, Vienna, Austria. monika.mustak@wienkav.at.
Thomas NothnaglDepartment of Medicine II, Centre for Rheumatology, Stockerau State Hospital, Stockerau, Austria. thomas.nothnagl@stockerau.lknoe.at.
Stephan E PuchnerDepartment of Orthopaedic Surgery, Medical University of Vienna, Vienna, Austria. stephan.puchner@meduniwien.ac.at.
Andrea Studnicka-BenkeDepartment of Internal Medicine III, Medical University of Salzburg, Salzburg, Austria. a.studnicka-benke@salk.at.
Burkhard F LeebRheumatology and Immunology Division, Department of Internal Medicine, Medical University of Graz, Graz, Austria. leeb.rheuma@aon.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA survey was conducted to evaluate whether a steady improvement in the quality of life of Rheumatoid Arthritis (RA) patients as frequently reported in clinical studies, does actually occur. The focus of this study laid on the personal perception of RA patients. How do patients who have been treated along accepted guidelines see the state of their health and their joint pain at different points in time?

methodsRA patients were asked to complete a questionnaire and return it to an opinion research centre. The questionnaire, which was developed by the authors, was divided into the areas: demography, symptom description and medical care, as well as the illness in a personal context. Three telephone interviews followed in monthly intervals when the patients' feelings about their illness, their every-day coping mechanisms and their social lives were rated. Intra-subject correlation and the level of agreement among patients when assessed at three different points within a two month period, was determined.

results127 patients replied to the questionnaire. RA exerts a significant impact on a patient's daily life. Average ratings of current state of health and joint pain (answered on a 5-part scale extending from 1 (very good) to 5 (very bad)) range between 2.6 and 2.9 all three times. However, intra-subject correlation between the different assessment times, is in general quite modest. Concerning the question: "How is your join pain today?" only 14 of 127 participants express identical ratings all three times , while in one third of the participants, a difference of two digits on the 5-part scale, at least twice had to be noticed. Intra-class correlation coefficients between answers at different points are often much smaller than 0.5. Results were similar in all subgroups analysed (men vs. women; patients receiving biologics vs. those not receiving biologics; disease duration ≤3 years vs. 4 to 10 years vs. ≥11 years).

conclusionOn an individual level personal assessments of health, well-being and joint pain are nevertheless unsteady even within the timeframe of two months. This is why, even now, RA patients still cannot plan their lives as non-affected people can.

Indexed as

Health StatusQuality of LifeActivities of Daily LivingAdaptation, PsychologicalAdultArthralgiaArthritis, RheumatoidAustriaCost of IllnessFemaleHealth Care SurveysHumansInterviews as TopicMaleMiddle AgedPain Measurement

Identifiers

PMID25943629
PMCPMC4427952

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.