Evidence map›Paper›PMID 25943596›Full record

ArticleJournal of oncology practice2015

Projected Clinical, Resource Use, and Fiscal Impacts of Implementing Low-Dose Computed Tomography Lung Cancer Screening in Medicare.

Joshua A Roth, Sean D Sullivan, Bernardo H L Goulart, Arliene Ravelo, Joanna C Sanderson, Scott D Ramsey

Open access · greenAbstract read
In one paragraph

Article in Journal of oncology practice, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Health Care Spending on Respiratory Diseases in the United States, 1996-2016.American journal of respiratory and critical care medicine · 2023
    Article
  4. Review
  5. Article
  6. Use of Lung Cancer Screening With Low-Dose Computed Tomography in the Medicare Population.Mayo Clinic proceedings. Innovations, quality & outcomes · 2019
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Lung Cancer Screening.The Medical clinics of North America · 2017
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Early detection of lung cancer.F1000Research · 2016
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Joshua A RothFred Hutchinson Cancer Research Center; University of Washington, Seattle; VeriTech, Mercer Island, WA; and Genentech, South San Francisco, CA jroth@fhcrc.org.
Sean D SullivanFred Hutchinson Cancer Research Center; University of Washington, Seattle; VeriTech, Mercer Island, WA; and Genentech, South San Francisco, CA.
Bernardo H L GoulartFred Hutchinson Cancer Research Center; University of Washington, Seattle; VeriTech, Mercer Island, WA; and Genentech, South San Francisco, CA.
Arliene RaveloFred Hutchinson Cancer Research Center; University of Washington, Seattle; VeriTech, Mercer Island, WA; and Genentech, South San Francisco, CA.
Joanna C SandersonFred Hutchinson Cancer Research Center; University of Washington, Seattle; VeriTech, Mercer Island, WA; and Genentech, South San Francisco, CA.
Scott D RamseyFred Hutchinson Cancer Research Center; University of Washington, Seattle; VeriTech, Mercer Island, WA; and Genentech, South San Francisco, CA.
Fred Hutch Cancer Center · US

Funding

UW Patient-Centered Outcomes Research Career Development Program K12 2014 2019K12HS022982 · AHRQ · UNIVERSITY OF WASHINGTON · PI SULLIVAN, SEAN D · 2014 to 2018
$3.8M
AHRQ HHS K12 HS022982AHRQ HHS K12HS022982
6 · The paper itself

Abstract

purposeThe Centers for Medicare and Medicaid Services (CMS) recently issued a national coverage determination that provides reimbursement for low-dose computed tomography (CT) lung cancer screening for enrollees age 55 to 77 years with ≥ 30-pack-year smoking history who currently smoke or quit in the last 15 years. The clinical, resource use, and fiscal impacts of this change in screening coverage policy remain uncertain.

methodsWe developed a simulation model to forecast the 5-year health outcome impacts of the CMS low-dose CT screening policy in Medicare compared with no screening. The model used data from the National Lung Screening Trial, CMS enrollment statistics and reimbursement schedules, and peer-reviewed literature. Outcomes included counts of screening examinations, patient cases of lung cancer detected, stage distribution, and total and per-enrollee per-month fiscal impact.

resultsOver 5 years, we project that low-dose CT screening will result in 10.7 million more low-dose CT scans, 52,000 more lung cancers detected, and increased overall expenditure of $6.8 billion ($2.22 per Medicare enrollee per month). The most fiscally impactful factors were the average cost-per-screening episode, proportion of enrollees eligible for screening, and cost of treating stage I lung cancer.

conclusionLow-dose CT screening is expected to increase lung cancer diagnoses, shift stage at diagnosis toward earlier stages, and substantially increase Medicare expenditures over a 5-year time horizon. These projections can inform planning efforts by Medicare administrators, contracted health care providers, and other stakeholders.

Indexed as

AgedComputer SimulationEarly Detection of CancerForecastingHealth Care CostsHealth PlanningHealth PolicyHealth ResourcesHumansLung NeoplasmsMedicareMiddle AgedModels, TheoreticalNeoplasm StagingRisk FactorsSmoking

Identifiers

PMID25943596
PMCPMC5706131
OpenAlexW2156348730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.